Iris Dror
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Explore the profile of Iris Dror including associated specialties, affiliations and a list of published articles.
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22
Citations
1222
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Recent Articles
1.
Dror I, Tan T, Plath K
Curr Opin Genet Dev
. 2024 Jul;
87:102235.
PMID: 39053028
To regulate gene expression, the macromolecular components of the mammalian interphase nucleus are spatially organized into a myriad of functional compartments. Over the past decade, increasingly sophisticated genomics, microscopy, and...
2.
Dror I, Chitiashvili T, Tan S, Cano C, Sahakyan A, Markaki Y, et al.
Cell
. 2024 Jan;
187(1):110-129.e31.
PMID: 38181737
X chromosome inactivation (XCI) serves as a paradigm for RNA-mediated regulation of gene expression, wherein the long non-coding RNA XIST spreads across the X chromosome in cis to mediate gene...
3.
Elkoshi N, Parikh S, Malcov-Brog H, Parikh R, Manich P, Netti F, et al.
J Invest Dermatol
. 2023 May;
143(12):2494-2506.e4.
PMID: 37236596
Skin pigmentation is paused after sun exposure; however, the mechanism behind this pausing is unknown. In this study, we found that the UVB-induced DNA repair system, led by the ataxia...
4.
Chitiashvili T, Hsu F, Dror I, Plath K, Clark A
Stem Cell Reports
. 2022 May;
17(6):1268-1278.
PMID: 35594860
Human germ cell development is a highly regulated process beginning soon after embryo implantation with the specification of primordial germ cells (PGCs) and ending in adulthood with the differentiation of...
5.
Markaki Y, Gan Chong J, Wang Y, Jacobson E, Luong C, Tan S, et al.
Cell
. 2021 Dec;
184(25):6212.
PMID: 34890555
No abstract available.
6.
Markaki Y, Gan Chong J, Wang Y, Jacobson E, Luong C, Tan S, et al.
Cell
. 2021 Nov;
184(25):6174-6192.e32.
PMID: 34813726
The lncRNA Xist forms ∼50 diffraction-limited foci to transcriptionally silence one X chromosome. How this small number of RNA foci and interacting proteins regulate a much larger number of X-linked...
7.
Chitiashvili T, Dror I, Kim R, Hsu F, Chaudhari R, Pandolfi E, et al.
Nat Cell Biol
. 2020 Dec;
22(12):1436-1446.
PMID: 33257808
X-chromosome dosage compensation in female placental mammals is achieved by X-chromosome inactivation (XCI). Human pre-implantation embryos are an exception, in which dosage compensation occurs by X-chromosome dampening (XCD). Here, we...
8.
Malcov-Brog H, Alpert A, Golan T, Parikh S, Nordlinger A, Netti F, et al.
Mol Cell
. 2018 Nov;
72(3):444-456.e7.
PMID: 30401431
Skin sun exposure induces two protection programs: stress responses and pigmentation, the former within minutes and the latter only hours afterward. Although serving the same physiological purpose, it is not...
9.
Sheinboim D, Maza I, Dror I, Parikh S, Krupalnik V, Bell R, et al.
Nat Commun
. 2017 Oct;
8(1):1022.
PMID: 29044103
Ectopic expression of lineage master regulators induces transdifferentiation. Whether cell fate transitions can be induced during various developmental stages has not been systemically examined. Here we discover that amongst different...
10.
Schone S, Jurk M, Bagherpoor Helabad M, Dror I, Lebars I, Kieffer B, et al.
Nat Commun
. 2016 Nov;
7:13784.
PMID: 27873998
No abstract available.