Iris de Rink
Overview
Explore the profile of Iris de Rink including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
22
Citations
989
Followers
0
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Recent Articles
11.
Aslam M, Alemdehy M, Hao B, Krijger P, Pritchard C, de Rink I, et al.
Proc Natl Acad Sci U S A
. 2020 Nov;
117(49):31343-31352.
PMID: 33229554
Development of progenitor B cells (ProB cells) into precursor B cells (PreB cells) is dictated by immunoglobulin heavy chain checkpoint (IgHCC), where the IgHC encoded by a productively rearranged allele...
12.
Ramovs V, Krotenberg Garcia A, Song J, de Rink I, Kreft M, Goldschmeding R, et al.
Life Sci Alliance
. 2020 May;
3(7).
PMID: 32423907
Epidermal-specific deletion of integrin α3β1 almost completely prevents the formation of papillomas during 7,12-Dimethylbenz[ ]anthracene/12- -tetradecanoylphorbol-13-acetate (DMBA/TPA) two-stage skin carcinogenesis. This dramatic decrease in tumorigenesis was thought to be due...
13.
Stelloo S, Linder S, Nevedomskaya E, Valle-Encinas E, de Rink I, Wessels L, et al.
Endocr Relat Cancer
. 2019 Dec;
27(2):67-79.
PMID: 31804970
Prostate cancer development and progression is largely dependent on androgen receptor (AR) signaling. AR is a hormone-dependent transcription factor, which binds to thousands of sites throughout the human genome to...
14.
Wellenstein M, Coffelt S, Duits D, van Miltenburg M, Slagter M, de Rink I, et al.
Nature
. 2019 Aug;
572(7770):538-542.
PMID: 31367040
Cancer-associated systemic inflammation is strongly linked to poor disease outcome in patients with cancer. For most human epithelial tumour types, high systemic neutrophil-to-lymphocyte ratios are associated with poor overall survival,...
15.
Xue Y, Meehan B, MacDonald E, Venneti S, Wang X, Witkowski L, et al.
Nat Commun
. 2019 Feb;
10(1):558.
PMID: 30718512
Inactivating mutations in SMARCA4 (BRG1), a key SWI/SNF chromatin remodelling gene, underlie small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). To reveal its druggable vulnerabilities, we perform kinase-focused RNAi...
16.
Kluin R, Kemper K, Kuilman T, de Ruiter J, Iyer V, Forment J, et al.
BMC Bioinformatics
. 2018 Oct;
19(1):366.
PMID: 30286710
Background: Mouse xenografts from (patient-derived) tumors (PDX) or tumor cell lines are widely used as models to study various biological and preclinical aspects of cancer. However, analyses of their RNA...
17.
Xiao Y, Palomero J, Grabowska J, Wang L, de Rink I, van Helvert L, et al.
Blood Adv
. 2018 Jan;
1(23):1993-2006.
PMID: 29296846
Monocytes/macrophages (MΦs), osteoclasts (OCs), and dendritic cells (DCs) are closely related cell types of high clinical significance, but the exact steps in their lineage commitment are unclear. In studies on...
18.
van der Kammen R, Song J, de Rink I, Janssen H, Madonna S, Scarponi C, et al.
Development
. 2017 Nov;
144(24):4588-4603.
PMID: 29113991
The Arp2/3 complex assembles branched actin filaments, which are key to many cellular processes, but its organismal roles remain poorly understood. Here, we employed conditional knockout mice to study the...
19.
Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora K, et al.
Cancer Cell
. 2016 Dec;
30(6):986.
PMID: 27960089
No abstract available.
20.
Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora K, et al.
Cancer Cell
. 2016 Oct;
30(4):548-562.
PMID: 27693046
Neuroblastoma is a pediatric embryonal malignancy characterized by impaired neuronal differentiation. A better understanding of neuroblastoma differentiation is essential for developing new therapeutic approaches. GDE2 (encoded by GDPD5) is a...