Iris Bruchhaus
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Explore the profile of Iris Bruchhaus including associated specialties, affiliations and a list of published articles.
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75
Citations
1646
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Recent Articles
11.
Raacke M, Kerr A, Dorpinghaus M, Brehmer J, Wu Y, Lorenzen S, et al.
Cells
. 2021 Aug;
10(7).
PMID: 34359826
Infections with the deadliest malaria parasite, , are accompanied by a strong immunological response of the human host. To date, more than 30 cytokines have been detected in elevated levels...
12.
Wu Y, Bouws P, Lorenzen S, Bruchhaus I, Metwally N
Methods Mol Biol
. 2021 Jul;
2369:187-197.
PMID: 34313990
During malaria infection, the endothelial lining of the small blood vessels of the brain and other vital organs is strongly stimulated. This leads to fatal complications and poor prognosis of...
13.
Wichers J, Tonkin-Hill G, Thye T, Krumkamp R, Kreuels B, Strauss J, et al.
Elife
. 2021 Apr;
10.
PMID: 33908865
Sequestration of ()-infected erythrocytes to host endothelium through the parasite-derived erythrocyte membrane protein 1 (EMP1) adhesion proteins is central to the development of malaria pathogenesis. EMP1 proteins have diversified and...
14.
Konig C, Honecker B, Wilson I, Weedall G, Hall N, Roeder T, et al.
Front Cell Infect Microbiol
. 2021 Apr;
11:641472.
PMID: 33816346
The human protozoan parasite can live in the human intestine for months or years without generating any symptoms in the host. For unknown reasons, amoebae can suddenly destroy the intestinal...
15.
Konig C, Meyer M, Lender C, Nehls S, Wallaschkowski T, Holm T, et al.
Microorganisms
. 2020 Oct;
8(10).
PMID: 33086693
Recently, a putative alcohol dehydrogenase 3, termed EhADH3B of the isolate HM-1:IMSS was identified, which is expressed at higher levels in non-pathogenic than in pathogenic amoebae and whose overexpression reduces...
16.
Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, et al.
Nat Commun
. 2020 Jul;
11(1):3459.
PMID: 32651360
Hepatic amebiasis, predominantly occurring in men, is a focal destruction of the liver due to the invading protozoan Entamoeba histolytica. Classical monocytes as well as testosterone are identified to have...
17.
Li Y, Romey-Glusing R, Tahan Zadeh N, von Frieling J, Hoffmann J, Huebbe P, et al.
Nutrients
. 2020 Apr;
12(4).
PMID: 32331413
Algal products are well known for their health promoting effects. Nonetheless, an in depth understanding of the underlying molecular mechanisms is still only fragmentary. Here, we show that aqueous furbelow...
18.
Lubiana P, Bouws P, Roth L, Dorpinghaus M, Rehn T, Brehmer J, et al.
Sci Rep
. 2020 Mar;
10(1):4548.
PMID: 32161335
Characterizing the adhesive dynamics of Plasmodium falciparum infected erythrocytes (IEs) to different endothelial cell receptors (ECRs) in flow is a big challenge considering available methods. This study investigated the adhesive...
19.
Dorpinghaus M, Furstenwerth F, Roth L, Bouws P, Rakotonirinalalao M, Jordan V, et al.
Microorganisms
. 2020 Jan;
8(2).
PMID: 31991814
Changes in the erythrocyte membrane induced by invasion allow cytoadhesion of infected erythrocytes (IEs) to the host endothelium, which can lead to severe complications. Binding to endothelial cell receptors (ECRs)...
20.
Wichers J, Scholz J, Strauss J, Witt S, Lill A, Ehnold L, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31363031
During its intraerythrocytic development, the malaria parasite exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain an infection. One family of small VSAs is the polymorphic STEVOR...