Irina Shelukhina
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Explore the profile of Irina Shelukhina including associated specialties, affiliations and a list of published articles.
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14
Citations
137
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Recent Articles
1.
Kost V, Sukhov D, Ivanov I, Kasheverov I, Ojomoko L, Shelukhina I, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069271
SLURP-1 is a three-finger human protein targeting nicotinic acetylcholine receptors (nAChRs). The recombinant forms of SLURP-1 produced in differ in added fusion fragments and in activity. The closest in sequence...
2.
Tsetlin V, Shelukhina I, Kozlov S, Kasheverov I
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762187
This review covers briefly the work carried out at our institute (IBCh), in many cases in collaboration with other Russian and foreign laboratories, for the last 50 years. It discusses...
3.
Shelukhina I, Siniavin A, Kasheverov I, Ojomoko L, Tsetlin V, Utkin Y
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047495
Nicotinic acetylcholine receptors (nAChRs) present as many different subtypes in the nervous and immune systems, muscles and on the cells of other organs. In the immune system, inflammation is regulated...
4.
Kasheverov I, Kudryavtsev D, Shelukhina I, Nikolaev G, Utkin Y, Tsetlin V
Biomolecules
. 2022 Feb;
12(2).
PMID: 35204690
The purpose of our review is to briefly show what different compounds of marine origin, from low molecular weight ones to peptides and proteins, offer for understanding the structure and...
5.
Tsetlin V, Haufe Y, Safronova V, Serov D, Shadamarshan P, Son L, et al.
Front Cell Neurosci
. 2022 Jan;
15:765541.
PMID: 35002625
Unlike most neuronal nicotinic acetylcholine receptor (nAChR) subunits, α7, α9, and α10 subunits are able to form functional homo- or heteromeric receptors without any β subunits. While the α7 subtype...
6.
Kovalchuk S, Ziganshin R, Shelukhina I
J Vis Exp
. 2021 Dec;
(178).
PMID: 34927617
Capillary ultra-high performance liquid chromatography (UHPLC) is currently a method of choice for the sample separation step in LC-MS-based proteomics. However, capillary columns are much less robust in comparison to...
7.
Manetti D, Garifulina A, Bartolucci G, Bazzicalupi C, Bellucci C, Chiaramonte N, et al.
J Med Chem
. 2019 Jan;
62(4):1887-1901.
PMID: 30681854
A three-dimensional database search has been applied to design a series of endo- and exo-3-(pyridin-3-yl)bicyclo[2.2.1]heptan-2-amines as nicotinic receptor ligands. The synthesized compounds were tested in radioligand binding assay on rat...
8.
Shelukhina I, Spirova E, Kudryavtsev D, Ojomoko L, Werner M, Methfessel C, et al.
PLoS One
. 2017 Aug;
12(8):e0181936.
PMID: 28797116
Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs) may shed light on their involvement in different physiological functions and diseases....
9.
Shelukhina I, Mikhailov N, Abushik P, Nurullin L, Nikolsky E, Giniatullin R
Front Neurol
. 2017 May;
8:163.
PMID: 28496430
Background: Parasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches. However, neurochemical mechanisms of cholinergic...
10.
Kilinc E, Guerrero-Toro C, Zakharov A, Vitale C, Gubert-Olive M, Koroleva K, et al.
Neuropharmacology
. 2016 Dec;
116:160-173.
PMID: 28025094
Serotonergic mechanisms play a central role in migraine pathology. However, the region-specific effects of serotonin (5-HT) mediated via multiple types of receptors in the nociceptive system are poorly understood. Using...