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Irina Miralda

Explore the profile of Irina Miralda including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 346
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Recent Articles
1.
Ozuna H, Bojja D, Partida-Sanchez S, Hall-Stoodley L, Amer A, Britt Jr R, et al.
Front Immunol . 2025 Feb; 16:1486784. PMID: 39935472
Background: CFTR modulator therapies have positive clinical outcomes, yet chronic inflammation and bacterial infections persist in people with CF (pwCF). How elexacaftor-tezacaftor-ivacaftor (ETI) fails to improve innate immune signaling responsible...
2.
Miralda I, Samanas N, Seo A, Foronda J, Sachen J, Hui Y, et al.
J Allergy Clin Immunol . 2023 Apr; 152(3):711-724.e14. PMID: 37100120
Background: Mast cell activation is critical for the development of allergic diseases. Ligation of sialic acid-binding immunoglobin-like lectins (Siglecs), such as Siglec-6, -7, and -8 as well as CD33, have...
3.
Samanas N, Murphy R, Miralda I, Hallstrand T, Piliponsky A
J Allergy Clin Immunol . 2022 Dec; 151(2):420-422. PMID: 36463980
No abstract available.
4.
Piliponsky A, Sharma K, Quach P, Brokaw A, Nguyen S, Orvis A, et al.
J Clin Invest . 2022 Aug; 132(20). PMID: 36006736
Invasive bacterial infections remain a major cause of human morbidity. Group B streptococcus (GBS) are Gram-positive bacteria that cause invasive infections in humans. Here, we show that factor XIIIA-deficient (FXIIIA-deficient)...
5.
Miralda I, Vashishta A, Rogers M, Lamont R, Uriarte S
Mol Microbiol . 2022 Apr; 117(6):1340-1351. PMID: 35437843
Periodontitis is a chronic inflammatory infectious disease that affects the integrity of tooth-supporting tissues and has adverse systemic consequences. Advances in sequencing technologies have uncovered organisms that are exclusively found...
6.
Saha S, Samanas N, Miralda I, Shubin N, Niino K, Bhise G, et al.
J Allergy Clin Immunol . 2021 Jul; 149(2):685-697. PMID: 34324892
Background: Mast cells are involved in many distinct pathologic conditions, suggesting that they recognize and respond to various stimuli and thus require a rich repertoire of cell surface proteins. However,...
7.
Miralda I, Uriarte S
Mol Oral Microbiol . 2020 Oct; 36(2):103-120. PMID: 33128827
Periodontitis is an irreversible, chronic inflammatory disease where inflammophilic pathogenic microbial communities accumulate in the gingival crevice. Neutrophils are a major component of the innate host response against bacterial challenge,...
8.
Miralda I, Vashishta A, Rogers M, Rouchka E, Li X, Waigel S, et al.
Front Immunol . 2020 May; 11:497. PMID: 32373107
Periodontitis is an irreversible, bacteria-induced, chronic inflammatory disease that compromises the integrity of tooth-supporting tissues and adversely affects systemic health. As the immune system's first line of defense against bacteria,...
9.
Miralda I, Klaes C, Graham J, Uriarte S
Pathogens . 2020 Feb; 9(2). PMID: 32075233
rarely causes disease in the immunocompetent, but reported cases of soft tissue infection describe abscess formation requiring surgical debridement for resolution. Neutrophils are the first innate immune cells to accumulate...
10.
Miralda I, Vashishta A, Uriarte S
Adv Exp Med Biol . 2019 Nov; 1197:165-178. PMID: 31732941
Periodontitis is a multifactorial chronic inflammatory infectious disease that compromises the integrity of tooth-supporting tissues. The disease progression depends on the disruption of host-microbe homeostasis in the periodontal tissue. This...