Irina Golovleva
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Explore the profile of Irina Golovleva including associated specialties, affiliations and a list of published articles.
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68
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769
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Recent Articles
11.
Vikberg A, Malla S, Golovleva I
Blood Cells Mol Dis
. 2020 Aug;
85:102483.
PMID: 32818800
Kinesin Family Member 23 (KIF23), a cell cycle regulator, has a key task in cytokinesis. KIF23 over-expression in cancer has been associated with tumor growth, progression, and poor prognosis, indicating...
12.
Haider Z, Landfors M, Golovleva I, Erlanson M, Schmiegelow K, Flaegstad T, et al.
Blood Cancer J
. 2020 Apr;
10(4):45.
PMID: 32345961
Despite having common overlapping immunophenotypic and morphological features, T-cell lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) have distinct clinical manifestations, which may represent separate diseases. We investigated and compared the epigenetic...
13.
Wu W, Johansson G, Wibom C, Brannstrom T, Malmstrom A, Henriksson R, et al.
Cancers (Basel)
. 2019 Dec;
11(12).
PMID: 31842352
Genome-wide association studies have identified 25 germline genetic loci that increase the risk of glioma. The somatic tumor molecular alterations, including -mutation status and 1p/19q co-deletion, have been included into...
14.
Jonsson F, Burstedt M, Kellgren T, Golovleva I
Mol Vis
. 2018 Nov;
24:667-678.
PMID: 30416333
Purpose: Retinitis pigmentosa (RP) represents a large group of inherited retinal diseases characterized by clinical and genetic heterogeneity. Among patients with RP in northern Sweden, we identified two severely affected...
15.
Weisschuh N, Stingl K, Audo I, Biskup S, Bocquet B, Branham K, et al.
Hum Mutat
. 2018 Aug;
39(10):1366-1371.
PMID: 30080950
Biallelic PDE6C mutations are a known cause for rod monochromacy, better known as autosomal recessive achromatopsia (ACHM), and early-onset cone photoreceptor dysfunction. PDE6C encodes the catalytic α'-subunit of the cone...
16.
Jonsson F, Westin I, Osterman L, Sandgren O, Burstedt M, Holmberg M, et al.
Acta Ophthalmol
. 2018 Feb;
96(7):737-743.
PMID: 29461686
Purpose: Inherited retinal dystrophies (IRDs) represent a group of progressive conditions affecting the retina. There is a great genetic heterogeneity causing IRDs, and to date, more than 260 genes are...
17.
Vikberg A, Vooder T, Lokk K, Annilo T, Golovleva I
Onco Targets Ther
. 2017 Oct;
10:4969-4979.
PMID: 29066916
KIF23 was recently suggested to be a potential molecular target for the treatment of lung cancer. This proposal is based on elevated expression of in several tumors affecting breast, lung,...
18.
Djusberg E, Jernberg E, Thysell E, Golovleva I, Lundberg P, Crnalic S, et al.
Prostate
. 2017 Feb;
77(6):625-638.
PMID: 28144969
Background: The relation between androgen receptor (AR) gene amplification and other mechanisms behind castration-resistant prostate cancer (CRPC), such as expression of constitutively active AR variants and steroid-converting enzymes has been...
19.
Ghasimi S, Wibom C, Dahlin A, Brannstrom T, Golovleva I, Andersson U, et al.
J Neurooncol
. 2016 Feb;
127(3):483-92.
PMID: 26839018
During the last years, genome wide association studies have discovered common germline genetic variants associated with specific glioma subtypes. We aimed to study the association between these germline risk variants...
20.
Olsson L, Ivanov Ofverholm I, Noren-Nystrom U, Zachariadis V, Nordlund J, Sjogren H, et al.
Br J Haematol
. 2015 May;
170(6):847-58.
PMID: 26018335
Paediatric B-cell precursor acute lymphoblastic leukaemias (BCP ALL) with IKZF1 deletions (∆IKZF1) are associated with a poor outcome. However, there are conflicting data as to whether ∆IKZF1 is an independent...