Irina Abnizova
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Explore the profile of Irina Abnizova including associated specialties, affiliations and a list of published articles.
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16
Citations
678
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Recent Articles
1.
Abnizova I, Stapel C, Boekhorst R, Lee J, Hemberg M
BMC Biol
. 2024 Apr;
22(1):78.
PMID: 38600550
Background: Regulation of transcription is central to the emergence of new cell types during development, and it often involves activation of genes via proximal and distal regulatory regions. The activity...
2.
King C, Fowler J, Abnizova I, Sood R, Hall M, Szeverenyi I, et al.
Nat Genet
. 2023 Aug;
55(9):1608.
PMID: 37626225
No abstract available.
3.
King C, Fowler J, Abnizova I, Sood R, Hall M, Szeverenyi I, et al.
Nat Genet
. 2023 Aug;
55(9):1440-1447.
PMID: 37537257
The incidence of keratinocyte cancer (basal cell and squamous cell carcinomas of the skin) is 17-fold lower in Singapore than the UK, despite Singapore receiving 2-3 times more ultraviolet (UV)...
4.
Abby E, Dentro S, Hall M, Fowler J, Ong S, Sood R, et al.
Nat Genet
. 2023 Jan;
55(2):232-245.
PMID: 36658434
NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations drive clonal expansion but impede carcinogenesis. Here...
5.
Murai K, Dentro S, Ong S, Sood R, Fernandez-Antoran D, Herms A, et al.
Nat Commun
. 2022 Oct;
13(1):6206.
PMID: 36266286
Aging normal human oesophagus accumulates TP53 mutant clones. These are the origin of most oesophageal squamous carcinomas, in which biallelic TP53 disruption is almost universal. However, how p53 mutant clones...
6.
Moody S, Senkin S, Islam S, Wang J, Nasrollahzadeh D, Penha R, et al.
Nat Genet
. 2021 Oct;
53(11):1553-1563.
PMID: 34663923
Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous...
7.
Abnizova I, Leonard S, Skelly T, Brown A, Jackson D, Gourtovaia M, et al.
J Bioinform Comput Biol
. 2012 Jul;
10(2):1241005.
PMID: 22809341
The new generation of short-read sequencing technologies requires reliable measures of data quality. Such measures are especially important for variant calling. However, in the particular case of SNP calling, a...
8.
Abnizova I, Skelly T, Naumenko F, Whiteford N, Brown C, Cox T
J Bioinform Comput Biol
. 2010 Jun;
8(3):579-91.
PMID: 20556863
As was the case in the beginning of the sequencing era, the new generation of short-read sequencing technologies still requires both accuracy of data processing methods and reliable measures of...
9.
Edwards Y, Walter K, McEwen G, Vavouri T, Kelly K, Abnizova I, et al.
Comp Biochem Physiol Part D Genomics Proteomics
. 2010 May;
1(1):46-58.
PMID: 20483234
We recently identified approximately 1400 conserved non-coding elements (CNEs) shared by the genomes of fugu (Takifugu rubripes) and human that appear to be associated with developmental regulation in vertebrates [Woolfe,...
10.
Whiteford N, Skelly T, Curtis C, Ritchie M, Lohr A, Zaranek A, et al.
Bioinformatics
. 2009 Jun;
25(17):2194-9.
PMID: 19549630
Motivation: Primary data analysis methods are of critical importance in second generation DNA sequencing. Improved methods have the potential to increase yield and reduce the error rates. Openly documented analysis...