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Irfan Zaidi

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Articles 33
Citations 614
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Recent Articles
1.
Fathi P, Alfonso A, Yek C, Putman Z, Drew M, Esposito D, et al.
Adv Sci (Weinh) . 2024 Oct; 12(1):e2403503. PMID: 39471070
Dynamic pathogen exposure may impact the immunological response to SARS-CoV-2 (SCV2). One potential explanation for the lack of severe SCV2-related morbidity and mortality in Southeast Asia is prior exposure to...
2.
Diawara H, Healy S, Mwakingwe-Omari A, Issiaka D, Diallo A, Traore S, et al.
Lancet Infect Dis . 2024 Aug; 24(12):1366-1382. PMID: 39153490
Background: Plasmodium falciparum parasitaemia during pregnancy causes maternal, fetal, and infant mortality. Poor pregnancy outcomes are related to blood-stage parasite sequestration and the ensuing inflammatory response in the placenta, which...
3.
Krajacich B, Samake D, Dao A, Diallo M, Sanogo Z, Yaro A, et al.
Front Epidemiol . 2024 Mar; 3:1243691. PMID: 38455906
Background: The spread of SARS-CoV-2 cannot be well monitored and understood in areas without capacity for effective disease surveillance. Countries with a young population will have disproportionately large numbers of...
4.
Ma R, Salinas N, Orr-Gonzalez S, Richardson B, Ouahes T, Torano H, et al.
PLoS Pathog . 2024 Mar; 20(3):e1011879. PMID: 38437239
Placental accumulation of Plasmodium falciparum infected erythrocytes results in maternal anemia, low birth weight, and pregnancy loss. The parasite protein VAR2CSA facilitates the accumulation of infected erythrocytes in the placenta...
5.
Jongo S, Church L, Milando F, Qassim M, Schindler T, Rashid M, et al.
J Clin Invest . 2024 Jan; 134(6). PMID: 38194272
BACKGROUNDSanaria PfSPZ Vaccine, composed of attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), protects against malaria. We conducted this clinical trial to assess the safety and efficacy of PfSPZ Vaccine in HIV-positive...
6.
Sagara I, Healy S, Assadou M, Kone M, Swihart B, Kwan J, et al.
Lancet Infect Dis . 2023 Jul; 23(11):1266-1279. PMID: 37499679
Background: Malaria transmission-blocking vaccines target mosquito-stage parasites and will support elimination programmes. Gamete vaccine Pfs230D1-EPA/Alhydrogel induced superior activity to zygote vaccine Pfs25-EPA/Alhydrogel in malaria-naive US adults. Here, we compared these...
7.
Rausch K, Barnafo E, Lambert L, Muratova O, Gorres J, Anderson C, et al.
iScience . 2023 Jul; 26(7):107192. PMID: 37485364
Malaria transmission-blocking vaccine candidates Pfs25-EPA and Pfs230D1-EPA target sexual stage development of parasites in the mosquito host, thereby reducing mosquito infectivity. When formulated on Alhydrogel, Pfs25-EPA has demonstrated safety and...
8.
Krajacich B, Samake D, Dao A, Diallo M, Sanogo Z, Yaro A, et al.
medRxiv . 2023 Jul; PMID: 37398491
The spread of SARS-CoV-2 cannot be well monitored and understood in areas without capacity for effective disease surveillance. Countries with a young population will have disproportionately large numbers of asymptomatic...
9.
Woodford J, Sagara I, Diawara H, Assadou M, Katile A, Attaher O, et al.
Front Immunol . 2022 Aug; 13:959697. PMID: 35990648
Malaria has been hypothesized as a factor that may have reduced the severity of the COVID-19 pandemic in sub-Saharan Africa. To evaluate the effect of recent malaria on COVID-19 we...
10.
Zaidi I, Duffy P
Med . 2022 May; 2(12):1289-1291. PMID: 35590146
In Kenya, the first trial of the attenuated whole organism PfSPZ Vaccine in infants has shown little efficacy against malaria infection, whereas trials in African adults have repeatedly observed protection....