Irena Bruzgo
Overview
Explore the profile of Irena Bruzgo including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
27
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Recent Articles
1.
Talalaj U, Uscinowicz P, Bruzgo I, Surazynski A, Zareba I, Markowska A
Molecules
. 2019 Oct;
24(20).
PMID: 31618846
KTTKS is a matrikine that originates from the proteolytic hydrolysis of collagen. This peptide stimulates ECM production and types I and III collagen expression in vitro. A more stable form...
2.
Purwin M, Markowska A, Bruzgo I, Rusak T, Surazynski A, Jaworowska U, et al.
Int J Pept Res Ther
. 2017 May;
23(2):235-245.
PMID: 28491013
Fifteen new peptide derivatives of ɛ-aminocaproic acid (EACA) containing the known fragment -Ala-Phe-Lys- with an affinity for plasmin were synthesised in the present study. The synthesis was carried out a...
3.
Puckowska A, Drozdowska D, Rusak M, Bielawski T, Bruzgo I, Midura-Nowaczek K
Acta Pol Pharm
. 2012 May;
69(1):63-73.
PMID: 22574508
The amino analogues of pentamidine with a polymethylene (n = 3 - 6) chain and their chlorambucil derivatives were synthesized. The obtained compounds revealed cytotoxic effect on MCF-7 human breast...
4.
Markowska A, Bruzgo I, Miltyk W, Midura-Nowaczek K
Protein Pept Lett
. 2010 Jul;
17(10):1300-4.
PMID: 20594155
Twelve peptides of the general X-SO(2)-D-Ser-Ala-Arg-OH formula (where X = methyl, phenyl, α-tolyl, p-tolyl, 4-methylbenzyl, 1-naphtyl, 2-naphtyl, 4-chlorophenyl, 4-bromophenyl, 2-mesityl, 2,4,6-triisopropylphenyl, 4-acetamidophenyl) were obtained and tested for their effect on...
5.
Drozdowska D, Bruzgo I, Midura-Nowaczek K
J Enzyme Inhib Med Chem
. 2010 May;
25(5):629-34.
PMID: 20429779
The biological evaluation of carbocyclic minor groove binders 1-6 is described. The cytotoxicity of the obtained compounds was tested on MDA-MB-231 breast cancer cells. The mechanism of action of compounds...
6.
Markowska A, Bruzgo I, Midura-Nowaczek K
J Enzyme Inhib Med Chem
. 2009 Dec;
25(1):139-42.
PMID: 20030517
Eleven peptides of the general formula H-d-Ser-Ala-Arg-NH-X, where X = (CH2)n-NH2, n = 2-9, (CH2)m-OH, m = 2-4, were obtained and tested for their effect on the amidolytic activities of...
7.
Bruzgo I, Midura-Nowaczek K, Kaczynska J, Krajewska D
Acta Pol Pharm
. 2009 Feb;
66(1):37-40.
PMID: 19226966
The effect of epsilon-aminocaproyl-S-benzyl-L-cysteine on the activation of plasminogen by t-PA. streptokinase and urokinase has been examined using fibrinolytic method. The obtained results have been compared with the obtained results...
8.
Puckowska A, Midura-Nowaczek K, Bruzgo I
Acta Pol Pharm
. 2008 Aug;
65(2):213-5.
PMID: 18666427
Inhibitory effects of nine carbocyclic DNA minor groove binders on amidolytic activities of plasmin, trypsin and urokinase were examined. Some of the studied compounds affected plasmin or trypsin activity, but...
9.
Midura-Nowaczek K, Lepietuszko I, Bruzgo I, Markowska A
Acta Pol Pharm
. 2008 Jul;
65(3):377-81.
PMID: 18646558
Five substituted amides of lysine with the general formula: X-Lys-NH-Y, where X= acetyl or ethoxycarbonyl, Y= cyclohexyl, benzyl, hexyl or cadaverine residue were synthesised and their effects on fibrinolytic activity...
10.
Bruzgo I, Midura-Nowaczek K
Acta Pol Pharm
. 2008 Jun;
64(5):479-82.
PMID: 18540170
No abstract available.