Inge M Ambros
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Explore the profile of Inge M Ambros including associated specialties, affiliations and a list of published articles.
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40
Citations
859
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Recent Articles
1.
Berner J, Weiss T, Sorger H, Rifatbegovic F, Kauer M, Windhager R, et al.
Glia
. 2022 Sep;
70(12):2361-2377.
PMID: 36054432
The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system. Reports on the interaction between...
2.
Martinez-Monleon A, Kryh Oberg H, Gaarder J, Berbegall A, Javanmardi N, Djos A, et al.
Sci Rep
. 2022 Jul;
12(1):12420.
PMID: 35859155
In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to characterize additional alterations that can function as prognostic and/or predictive markers....
3.
Schmelz K, Toedling J, Huska M, Cwikla M, Kruetzfeldt L, Proba J, et al.
Nat Commun
. 2021 Nov;
12(1):6804.
PMID: 34815394
Intratumour heterogeneity is a major cause of treatment failure in cancer. We present in-depth analyses combining transcriptomic and genomic profiling with ultra-deep targeted sequencing of multiregional biopsies in 10 patients...
4.
Lazic D, Kromp F, Rifatbegovic F, Repiscak P, Kirr M, Mivalt F, et al.
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503120
While the bone marrow attracts tumor cells in many solid cancers leading to poor outcome in affected patients, comprehensive analyses of bone marrow metastases have not been performed on a...
5.
Peneder P, Stutz A, Surdez D, Krumbholz M, Semper S, Chicard M, et al.
Nat Commun
. 2021 May;
12(1):3230.
PMID: 34050156
Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring. To unlock liquid...
6.
Kromp F, Fischer L, Bozsaky E, Ambros I, Dorr W, Beiske K, et al.
IEEE Trans Med Imaging
. 2021 Mar;
40(7):1934-1949.
PMID: 33784615
Separating and labeling each nuclear instance (instance-aware segmentation) is the key challenge in nuclear image segmentation. Deep Convolutional Neural Networks have been demonstrated to solve nuclear image segmentation tasks across...
7.
Weiss T, Taschner-Mandl S, Janker L, Bileck A, Rifatbegovic F, Kromp F, et al.
Nat Commun
. 2021 Mar;
12(1):1624.
PMID: 33712610
Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity allows SCs to acquire repair-specific functions essential for peripheral nerve regeneration. Here, we investigate whether stromal SCs in benign-behaving...
8.
Fiedler S, Ambros I, Glogova E, Benesch M, Urban C, Mayer M, et al.
Cancers (Basel)
. 2021 Feb;
13(3).
PMID: 33540616
We evaluated long-term outcome and genomic profiles in the Austrian Neuroblastoma Trial A-NB94 which applied a risk-adapted strategy of treatment (RAST) using stage, age and amplification (MNA) status for stratification....
9.
Ambros I, Tonini G, Potschger U, Gross N, Mosseri V, Beiske K, et al.
J Clin Oncol
. 2020 Sep;
38(31):3685-3697.
PMID: 32903140
Purpose: For localized, resectable neuroblastoma without amplification, surgery only is recommended even if incomplete. However, it is not known whether the genomic background of these tumors may influence outcome. Patients...
10.
Kromp F, Bozsaky E, Rifatbegovic F, Fischer L, Ambros M, Berneder M, et al.
Sci Data
. 2020 Aug;
7(1):262.
PMID: 32782410
Fully-automated nuclear image segmentation is the prerequisite to ensure statistically significant, quantitative analyses of tissue preparations,applied in digital pathology or quantitative microscopy. The design of segmentation methods that work independently...