Peter F Ambros
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Explore the profile of Peter F Ambros including associated specialties, affiliations and a list of published articles.
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86
Citations
4160
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Recent Articles
1.
Flaadt T, Ladenstein R, Ebinger M, Lode H, Arnardottir H, Poetschger U, et al.
J Clin Oncol
. 2023 Feb;
41(17):3135-3148.
PMID: 36854071
Purpose: Patients with relapsed high-risk neuroblastoma (rHR-NB) have a poor prognosis. We hypothesized that graft-versus-neuroblastoma effects could be elicited by transplantation of haploidentical stem cells (haplo-SCT) exploiting cytotoxic functions of...
2.
Berner J, Weiss T, Sorger H, Rifatbegovic F, Kauer M, Windhager R, et al.
Glia
. 2022 Sep;
70(12):2361-2377.
PMID: 36054432
The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system. Reports on the interaction between...
3.
Martinez-Monleon A, Kryh Oberg H, Gaarder J, Berbegall A, Javanmardi N, Djos A, et al.
Sci Rep
. 2022 Jul;
12(1):12420.
PMID: 35859155
In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to characterize additional alterations that can function as prognostic and/or predictive markers....
4.
Schmelz K, Toedling J, Huska M, Cwikla M, Kruetzfeldt L, Proba J, et al.
Nat Commun
. 2021 Nov;
12(1):6804.
PMID: 34815394
Intratumour heterogeneity is a major cause of treatment failure in cancer. We present in-depth analyses combining transcriptomic and genomic profiling with ultra-deep targeted sequencing of multiregional biopsies in 10 patients...
5.
Schriegel F, Taschner-Mandl S, Bernkopf M, Grunwald U, Siebert N, Ambros P, et al.
J Cancer Res Clin Oncol
. 2021 Oct;
148(10):2581-2588.
PMID: 34623519
Purpose: Neuroblastoma (NB) is the most frequent extracranial tumor in children. The detection of bone marrow (BM) involvement is crucial for correct staging and risk-adapted treatment. We compared three methods...
6.
Lazic D, Kromp F, Rifatbegovic F, Repiscak P, Kirr M, Mivalt F, et al.
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503120
While the bone marrow attracts tumor cells in many solid cancers leading to poor outcome in affected patients, comprehensive analyses of bone marrow metastases have not been performed on a...
7.
Bellini A, Potschger U, Bernard V, Lapouble E, Baulande S, Ambros P, et al.
J Clin Oncol
. 2021 Jun;
39(30):3377-3390.
PMID: 34115544
Purpose: In neuroblastoma (NB), the ALK receptor tyrosine kinase can be constitutively activated through activating point mutations or genomic amplification. We studied genetic alterations in high-risk (HR) patients on the...
8.
Peneder P, Stutz A, Surdez D, Krumbholz M, Semper S, Chicard M, et al.
Nat Commun
. 2021 May;
12(1):3230.
PMID: 34050156
Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring. To unlock liquid...
9.
Kromp F, Fischer L, Bozsaky E, Ambros I, Dorr W, Beiske K, et al.
IEEE Trans Med Imaging
. 2021 Mar;
40(7):1934-1949.
PMID: 33784615
Separating and labeling each nuclear instance (instance-aware segmentation) is the key challenge in nuclear image segmentation. Deep Convolutional Neural Networks have been demonstrated to solve nuclear image segmentation tasks across...
10.
Weiss T, Taschner-Mandl S, Janker L, Bileck A, Rifatbegovic F, Kromp F, et al.
Nat Commun
. 2021 Mar;
12(1):1624.
PMID: 33712610
Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity allows SCs to acquire repair-specific functions essential for peripheral nerve regeneration. Here, we investigate whether stromal SCs in benign-behaving...