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Inder M Verma

Explore the profile of Inder M Verma including associated specialties, affiliations and a list of published articles. Areas
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Articles 164
Citations 13904
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Recent Articles
1.
Hara T, Chanoch-Myers R, Mathewson N, Myskiw C, Atta L, Bussema L, et al.
Cancer Cell . 2021 Jun; 39(6):779-792.e11. PMID: 34087162
The mesenchymal subtype of glioblastoma is thought to be determined by both cancer cell-intrinsic alterations and extrinsic cellular interactions, but remains poorly understood. Here, we dissect glioblastoma-to-microenvironment interactions by single-cell...
2.
Neftel C, Laffy J, Filbin M, Hara T, Shore M, Rahme G, et al.
Cell . 2019 Jul; 178(4):835-849.e21. PMID: 31327527
Diverse genetic, epigenetic, and developmental programs drive glioblastoma, an incurable and poorly understood tumor, but their precise characterization remains challenging. Here, we use an integrative approach spanning single-cell RNA-sequencing of...
3.
Hara T, Verma I
Cancer Res . 2019 Jul; 79(15):3983-3991. PMID: 31315836
Development of animal models to investigate the complex ecosystem of malignant gliomas using the Cre/loxP recombination system has significantly contributed to our understanding of the molecular underpinnings of this deadly...
4.
Masnadi-Shirazi M, Maurya M, Pao G, Ke E, Verma I, Subramaniam S
BMC Bioinformatics . 2019 May; 20(1):294. PMID: 31142274
Background: Biochemical networks are often described through static or time-averaged measurements of the component macromolecules. Temporal variation in these components plays an important role in both describing the dynamical nature...
5.
Verma S, Yeddula N, Soda Y, Zhu Q, Pao G, Moresco J, et al.
Proc Natl Acad Sci U S A . 2019 Mar; 116(15):7363-7370. PMID: 30918126
Coordination of growth and genomic stability is critical for normal cell physiology. Although the E3 ubiquitin ligase BRCA1 is a key player in maintenance of genomic stability, its role in...
6.
Verma S, De Jesus P, Chanda S, Verma I
Mol Cell Biol . 2018 Nov; 39(3). PMID: 30397075
The nuclear factor kappa B (NF-κB) family of transcription factors plays a central role in coordinating the expression of genes that control inflammation, immune responses, cell proliferation, and a variety...
7.
Mazor R, Friedmann-Morvinski D, Alsaigh T, Kleifeld O, Kistler E, Rousso-Noori L, et al.
Sci Transl Med . 2018 Aug; 10(455). PMID: 30135249
Obesity and related morbidities pose a major health threat. Obesity is associated with increased blood concentrations of the anorexigenic hormone leptin; however, obese individuals are resistant to its anorexigenic effects....
8.
Zhu Q, Hoong N, Aslanian A, Hara T, Benner C, Heinz S, et al.
Mol Cell . 2018 Jun; 70(5):842-853.e7. PMID: 29861157
Heterochromatic repetitive satellite RNAs are extensively transcribed in a variety of human cancers, including BRCA1 mutant breast cancer. Aberrant expression of satellite RNAs in cultured cells induces the DNA damage...
9.
Ramaswamy S, Tonnu N, Menon T, Lewis B, Green K, Wampler D, et al.
Cell Rep . 2018 May; 23(5):1565-1580. PMID: 29719266
Hemophilia B is an ideal target for gene- and cell-based therapies because of its monogenic nature and broad therapeutic index. Here, we demonstrate the use of cell therapy as a...
10.
Ogawa J, Pao G, Shokhirev M, Verma I
Cell Rep . 2018 Apr; 23(4):1220-1229. PMID: 29694897
We have developed a cancer model of gliomas in human cerebral organoids that allows direct observation of tumor initiation as well as continuous microscopic observations. We used CRISPR/Cas9 technology to...