Ilse D Jacobsen
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Explore the profile of Ilse D Jacobsen including associated specialties, affiliations and a list of published articles.
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114
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3136
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Recent Articles
1.
Kapitan M, Niemiec M, Millet N, Brandt P, Chowdhury M, Czapka A, et al.
bioRxiv
. 2024 Sep;
PMID: 39314435
The fungus and the Gram-positive bacterium share mucosal niches in the human body. As opportunistic pathogens, both are found to expand population size during dysbiosis, and can cause severe systemic...
2.
Bottcher B, Kienast S, Leufken J, Eggers C, Sharma P, Leufken C, et al.
Microbiol Spectr
. 2024 Apr;
12(5):e0425522.
PMID: 38587411
tRNA modifications play important roles in maintaining translation accuracy in all domains of life. Disruptions in the tRNA modification machinery, especially of the anticodon stem loop, can be lethal for...
3.
Jungnickel B, Jacobsen I
Front Fungal Biol
. 2023 Sep;
3:940884.
PMID: 37746206
Animal models are essential to understand the pathophysiology of infections, to test novel antifungal compounds, and to determine the potential of adjunctive therapies, e.g. immune modulation. The murine model of...
4.
Rebai Y, Wagner L, Gnaien M, Hammer M, Kapitan M, Niemiec M, et al.
Microorganisms
. 2023 Aug;
11(8).
PMID: 37630490
is a pathobiont of the gastrointestinal tract. It can contribute to the diversity of the gut microbiome without causing harmful effects. When the immune system is compromised, can damage intestinal...
5.
Langenhorst D, Furst A, Alberter K, Vilhena C, Dasari P, Daud M, et al.
J Immunol
. 2023 Jul;
211(5):804-815.
PMID: 37436030
Because of the growing numbers of immunocompromised patients, the incidence of life-threatening fungal infections caused by Candida albicans and Aspergillus fumigatus is increasing. We have recently identified enolase 1 (Eno1)...
6.
Refisch A, Sen Z, Klassert T, Busch A, Besteher B, Danyeli L, et al.
Neuropharmacology
. 2023 May;
235:109568.
PMID: 37182790
Depression is highly prevalent (6% 1-year prevalence) and is the second leading cause of disability worldwide. Available treatment options for depression are far from optimal, with response rates only around...
7.
Jacobsen I
Curr Clin Microbiol Rep
. 2023 May;
10(2):55-65.
PMID: 37151578
Abstract: Purpose Of Review: The fungus has evolved to live in close association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy humans. As an opportunistic pathogen,...
8.
Jacobsen I
Methods Mol Biol
. 2023 May;
2667:181-196.
PMID: 37145285
Animal models have been crucial in understanding the pathogenesis and developing novel therapeutic approaches for fungal infections in general. This is especially true for mucormycosis, which has a low incidence...
9.
Niemiec M, Kapitan M, Himmel M, Doll K, Kruger T, Kollner T, et al.
Front Cell Infect Microbiol
. 2022 Jun;
12:866416.
PMID: 35651758
The human gut acts as the main reservoir of microbes and a relevant source of life-threatening infections, especially in immunocompromised patients. There, the opportunistic fungal pathogen adapts to the host...
10.
Mentrup T, Stumpff-Niggemann A, Leinung N, Schlosser C, Schubert K, Wehner R, et al.
Nat Commun
. 2022 Apr;
13(1):1880.
PMID: 35388002
Sensing of pathogens by pattern recognition receptors (PRR) is critical to initiate protective host defence reactions. However, activation of the immune system has to be carefully titrated to avoid tissue...