Ilse D Jacobsen
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Explore the profile of Ilse D Jacobsen including associated specialties, affiliations and a list of published articles.
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114
Citations
3136
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Recent Articles
11.
Ramirez-Zavala B, Kruger I, Dunker C, Jacobsen I, Morschhauser J
PLoS Pathog
. 2022 Feb;
18(2):e1010283.
PMID: 35108336
Protein kinases play central roles in virtually all signaling pathways that enable organisms to adapt to their environment. Microbial pathogens must cope with severely restricted iron availability in mammalian hosts...
12.
Wich M, Greim S, Ferreira-Gomes M, Kruger T, Kniemeyer O, Brakhage A, et al.
Virulence
. 2021 Dec;
12(1):3137-3148.
PMID: 34923920
is a common commensal on human mucosal surfaces, but can become pathogenic, e.g. if the host is immunocompromised. While neutrophils, macrophages and T cells are regarded as major players in...
13.
Ferreira-Gomes M, Wich M, Bode S, Hube B, Jacobsen I, Jungnickel B
Front Immunol
. 2021 Nov;
12:698849.
PMID: 34819929
is usually a benign member of the human gut microbiota, but can become pathogenic under certain circumstances, for example in an immunocompromised host. The innate immune system, in particular neutrophils...
14.
Polke M, Jacobsen I
Bio Protoc
. 2021 Oct;
7(19):e2562.
PMID: 34595247
Here, we describe a protocol for a continuous flow system for cultures growing adherent to a plastic surface. The protocol was adapted from a previous method established to simulate blood...
15.
Dunker C, Polke M, Schulze-Richter B, Schubert K, Rudolphi S, Gressler A, et al.
Nat Commun
. 2021 Jun;
12(1):3899.
PMID: 34162849
The ability of the fungal pathogen Candida albicans to undergo a yeast-to-hypha transition is believed to be a key virulence factor, as filaments mediate tissue damage. Here, we show that...
16.
Machata S, Sreekantapuram S, Hunniger K, Kurzai O, Dunker C, Schubert K, et al.
Front Immunol
. 2021 Feb;
11:565869.
PMID: 33519798
Murine infection models are widely used to study systemic candidiasis caused by . Whole-blood models can help to elucidate host-pathogens interactions and have been used for several species in human...
17.
von Muller C, Bulman F, Wagner L, Rosenberger D, Marolda A, Kurzai O, et al.
Sci Rep
. 2020 Dec;
10(1):21818.
PMID: 33311597
Burn wounds are highly susceptible sites for colonization and infection by bacteria and fungi. Large wound surface, impaired local immunity, and broad-spectrum antibiotic therapy support growth of opportunistic fungi such...
18.
dEnfert C, Kaune A, Alaban L, Chakraborty S, Cole N, Delavy M, et al.
FEMS Microbiol Rev
. 2020 Nov;
45(3).
PMID: 33232448
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral cavity, gut or genital tract of most individuals, constrained by the local microbiota,...
19.
Machata S, Muller M, Lehmann R, Sieber P, Panagiotou G, Carvalho A, et al.
Virulence
. 2020 Oct;
11(1):1337-1351.
PMID: 33043780
Invasive pulmonary aspergillosis (IPA) is a severe infection that is difficult to diagnose due to the ubiquitous presence of fungal spores, the underlying diseases of risk patients, and limitations of...
20.
Gerwien F, Dunker C, Brandt P, Garbe E, Jacobsen I, Vylkova S
mSphere
. 2020 Aug;
5(4).
PMID: 32817377
Typically, established lab strains are widely used to study host-pathogen interactions. However, to better reflect the infection process, the experimental use of clinical isolates has come more into focus. Here,...