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Ildar Gabaev

Explore the profile of Ildar Gabaev including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 239
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Recent Articles
1.
Shilts J, Crozier T, Teixeira-Silva A, Gabaev I, Pereyra Gerber P, Greenwood E, et al.
PLoS Biol . 2023 Feb; 21(2):e3001959. PMID: 36735681
The interactions between Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and human host factors enable the virus to propagate infections that lead to Coronavirus Disease 2019 (COVID-19). The spike protein...
2.
Crozier T, Greenwood E, Williamson J, Guo W, Porter L, Gabaev I, et al.
Wellcome Open Res . 2022 Dec; 7:224. PMID: 36483314
Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected...
3.
Pereyra Gerber P, Duncan L, Greenwood E, Marelli S, Naamati A, Teixeira-Silva A, et al.
PLoS Pathog . 2022 Feb; 18(2):e1010265. PMID: 35143592
Efforts to define serological correlates of protection against COVID-19 have been hampered by the lack of a simple, scalable, standardised assay for SARS-CoV-2 infection and antibody neutralisation. Plaque assays remain...
4.
Gabaev I, Williamson J, Crozier T, Schulz T, Lehner P
Cell Rep . 2020 Oct; 33(2):108249. PMID: 33053346
Kaposi's sarcoma herpesvirus (KSHV) is an oncogenic human virus and the leading cause of mortality in HIV infection. KSHV reactivation from latent- to lytic-stage infection initiates a cascade of viral...
5.
Elbasani E, Gramolelli S, Gunther T, Gabaev I, Grundhoff A, Ojala P
J Virol . 2020 Apr; 94(13). PMID: 32295923
The anaphase-promoting complex, or cyclosome (APC/C), is a large E3 ubiquitin ligase composed of 14 subunits. The activity of APC/C oscillates during the cell cycle to ensure a timely transition...
6.
Perez-Carmona N, Martinez-Vicente P, Farre D, Gabaev I, Messerle M, Engel P, et al.
J Virol . 2018 Feb; 92(9). PMID: 29467314
Human cytomegalovirus (HCMV) persistence in infected individuals relies on a plethora of mechanisms to efficiently reduce host immune responses. To that end, HCMV uses a variety of gene products, some...
7.
Zischke J, Mamareli P, Pokoyski C, Gabaev I, Buyny S, Jacobs R, et al.
PLoS Pathog . 2017 Jun; 13(6):e1006454. PMID: 28628650
Human Cytomegalovirus (HCMV) is a widespread pathogen, infection with which can cause severe disease for immunocompromised individuals. The complex changes wrought on the host's immune system during both productive and...
8.
Daenthanasanmak A, Salguero G, Sundarasetty B, Waskow C, Cosgun K, Guzman C, et al.
Mol Ther Methods Clin Dev . 2015 Jun; 1:14060. PMID: 26052526
Human cytomegalovirus (HCMV) harmfully impacts survival after peripheral blood hematopoietic stem cell transplantation (PB-HSCT). Delayed immune reconstitution after cord blood (CB)-HSCT leads to even higher HCMV-related morbidity and mortality. Towards...
9.
Gabaev I, Elbasani E, Ameres S, Steinbruck L, Stanton R, Doring M, et al.
J Virol . 2014 Oct; 88(24):14326-39. PMID: 25275132
Unlabelled: The human cytomegalovirus (CMV) UL11 open reading frame (ORF) encodes a putative type I transmembrane glycoprotein which displays remarkable amino acid sequence variability among different CMV isolates, suggesting that...
10.
Elbasani E, Gabaev I, Steinbruck L, Messerle M, Borst E
Viruses . 2014 Jan; 6(1):354-70. PMID: 24452007
Human cytomegalovirus (HCMV) has a large 240 kb genome that may encode more than 700 gene products with many of them remaining uncharacterized. Mutagenesis of bacterial artificial chromosome (BAC)-cloned CMV...