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Ilaria Piccialli

Explore the profile of Ilaria Piccialli including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 197
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Recent Articles
1.
Falanga A, Piccialli I, Greco F, DErrico S, Nolli M, Borbone N, et al.
J Neurochem . 2025 Jan; 169(1):e16296. PMID: 39829311
The natural compound orotic acid and its anionic form, orotate, play a pivotal role in various biological processes, serving as essential intermediates in pyrimidine de novo synthesis, with demonstrated connections...
2.
Gamberi C, Leverette C, Davis A, Ismail M, Piccialli I, Borbone N, et al.
Vaccines (Basel) . 2024 Nov; 12(11). PMID: 39591167
The vast, untapped potential of the world's oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as spp. and are emerging as resources for recombinant vaccine development...
3.
Falanga A, Greco F, Terracciano M, DErrico S, Marzano M, Feola S, et al.
Int J Pharm . 2024 Nov; 668:124941. PMID: 39532274
Cancer immunotherapy is focused on stimulating the immune system against cancer cells by exploiting immune checkpoint mechanisms. PD-1/PD-L1 is one of the most known immune checkpoints due to the widespread...
4.
Magliocca G, Esposito E, Tufano M, Piccialli I, Rubino V, Tedeschi V, et al.
Antioxidants (Basel) . 2024 Aug; 13(8). PMID: 39199246
Parkinson's disease (PD), the second most common neurodegenerative disease in the elderly, is characterized by selective loss of dopaminergic neurons and accumulation of α-synuclein (α-syn), mitochondrial dysfunction, Ca dyshomeostasis, and...
5.
Piccialli I, Greco F, Roviello G, Sisalli M, Tedeschi V, Di Mola A, et al.
Biomed Pharmacother . 2023 Oct; 168:115745. PMID: 37871561
Amyloid β 1-42 (Aβ) protein aggregation is considered one of the main triggers of Alzheimer's disease (AD). In this study, we examined the in vitro anti-amyloidogenic activity of the isoindolinone...
6.
Sapienza S, Tedeschi V, Apicella B, Palestra F, Russo C, Piccialli I, et al.
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36361823
Background: An emerging body of evidence indicates an association between anthropogenic particulate matter (PM) and neurodegeneration. Although the historical focus of PM toxicity has been on the cardiopulmonary system, ultrafine...
7.
Piccialli I, Sisalli M, de Rosa V, Boscia F, Tedeschi V, Secondo A, et al.
Cells . 2022 Sep; 11(18). PMID: 36139395
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions. Cortical and hippocampal hyperexcitability intervenes in the pathological derangement of brain activity leading to cognitive...
8.
Piccialli I, Tedeschi V, Caputo L, DErrico S, Ciccone R, De Feo V, et al.
Front Pharmacol . 2022 May; 13:876614. PMID: 35600880
Alzheimer's disease (AD) is a chronic, complex neurodegenerative disorder mainly characterized by the irreversible loss of memory and cognitive functions. Different hypotheses have been proposed thus far to explain the...
9.
Greco F, Musumeci D, Borbone N, Falanga A, DErrico S, Terracciano M, et al.
Molecules . 2022 May; 27(9). PMID: 35566347
Trans-polydatin (tPD), the 3-β-D-glucoside of the well-known nutraceutical trans-resveratrol, is a natural polyphenol with documented anti-cancer, anti-inflammatory, cardioprotective, and immunoregulatory effects. Considering the anticancer activity of tPD, in this work,...
10.
Borbone N, Piccialli I, Falanga A, Piccialli V, Roviello G, Oliviero G
Int J Mol Sci . 2022 Apr; 23(8). PMID: 35457177
The recent development of mRNA vaccines against the SARS-CoV-2 infection has turned the spotlight on the potential of nucleic acids as innovative prophylactic agents and as diagnostic and therapeutic tools....