Agnese Secondo
Overview
Explore the profile of Agnese Secondo including associated specialties, affiliations and a list of published articles.
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Articles
111
Citations
1520
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Recent Articles
1.
Amiranda S, Succoio M, Anzilotti S, Cuomo O, Petrozziello T, Tedeschi V, et al.
Heliyon
. 2025 Mar;
11(4):e42457.
PMID: 40028587
Carbonic anhydrases constitute a family of metalloenzymes vital for maintaining acid-base balance and regulating pH in physio-pathological processes. These findings suggest carbonic anhydrases as potential therapeutic targets for treating pH-associated...
2.
Tedeschi V, Nele V, Valsecchi V, Anzilotti S, Vinciguerra A, Zucaro L, et al.
Pharmacol Res
. 2024 Nov;
210:107491.
PMID: 39491634
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease currently incurable, in which motor neuron degeneration leads to voluntary skeletal muscle atrophy. Molecularly, ALS is characterized by protein aggregation, synaptic...
3.
Magliocca G, Esposito E, Tufano M, Piccialli I, Rubino V, Tedeschi V, et al.
Antioxidants (Basel)
. 2024 Aug;
13(8).
PMID: 39199246
Parkinson's disease (PD), the second most common neurodegenerative disease in the elderly, is characterized by selective loss of dopaminergic neurons and accumulation of α-synuclein (α-syn), mitochondrial dysfunction, Ca dyshomeostasis, and...
4.
Merlino F, Secondo A, Mitidieri E, Sorrentino R, Bellavita R, Grasso N, et al.
J Med Chem
. 2024 Aug;
67(16):13879-13890.
PMID: 39096311
While the urotensinergic system plays a role in influencing various pathologies, its potential remains untapped because of the absence of therapeutically effective urotensin II receptor (UTR) modulators. Herein, we developed...
5.
Tedeschi V, Sapienza S, Ciancio R, Canzoniero L, Pannaccione A, Secondo A
Curr Neuropharmacol
. 2024 May;
PMID: 38766825
Besides controlling several organellar functions, lysosomal channels also guide the catabolic "self-eating" process named autophagy, which is mainly involved in protein and organelle quality control. Neuronal cells are particularly sensitive...
6.
Cantone A, Burgaletto C, Di Benedetto G, Pannaccione A, Secondo A, Bellanca C, et al.
Cells
. 2024 Feb;
13(4.
PMID: 38391922
Alzheimer's disease (AD), marked by cognitive impairment, predominantly affects the brain regions regulated by cholinergic innervation, such as the cerebral cortex and hippocampus. Cholinergic dysfunction, a key contributor to age-related...
7.
Sapienza S, Tedeschi V, Apicella B, Pannaccione A, Russo C, Sisalli M, et al.
Ecotoxicol Environ Saf
. 2024 Feb;
273:116104.
PMID: 38377779
Increased risk of neurodegenerative diseases has been envisaged for air pollution exposure. On the other hand, environmental risk factors, including air pollution, have been suggested for Amyotrophic Lateral Sclerosis (ALS)...
8.
Martin-Romero F, Secondo A, Gruszczynska-Biegala J
Front Cell Neurosci
. 2023 Oct;
17:1300412.
PMID: 37876915
No abstract available.
9.
Piccialli I, Greco F, Roviello G, Sisalli M, Tedeschi V, Di Mola A, et al.
Biomed Pharmacother
. 2023 Oct;
168:115745.
PMID: 37871561
Amyloid β 1-42 (Aβ) protein aggregation is considered one of the main triggers of Alzheimer's disease (AD). In this study, we examined the in vitro anti-amyloidogenic activity of the isoindolinone...
10.
Nele V, Tedeschi V, Campani V, Ciancio R, Angelillo A, Graziano S, et al.
Antioxidants (Basel)
. 2023 Feb;
12(2).
PMID: 36829918
Neurodegenerative diseases are characterized by mitochondrial dysfunction leading to abnormal levels of reactive oxygen species (ROS), making the use of ROS-scavenging nanomaterials a promising therapeutic approach. Here, we combined the...