Anna Pannaccione
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Explore the profile of Anna Pannaccione including associated specialties, affiliations and a list of published articles.
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56
Citations
789
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Recent Articles
1.
Tedeschi V, Nele V, Valsecchi V, Anzilotti S, Vinciguerra A, Zucaro L, et al.
Pharmacol Res
. 2024 Nov;
210:107491.
PMID: 39491634
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease currently incurable, in which motor neuron degeneration leads to voluntary skeletal muscle atrophy. Molecularly, ALS is characterized by protein aggregation, synaptic...
2.
Magliocca G, Esposito E, Tufano M, Piccialli I, Rubino V, Tedeschi V, et al.
Antioxidants (Basel)
. 2024 Aug;
13(8).
PMID: 39199246
Parkinson's disease (PD), the second most common neurodegenerative disease in the elderly, is characterized by selective loss of dopaminergic neurons and accumulation of α-synuclein (α-syn), mitochondrial dysfunction, Ca dyshomeostasis, and...
3.
Merlino F, Secondo A, Mitidieri E, Sorrentino R, Bellavita R, Grasso N, et al.
J Med Chem
. 2024 Aug;
67(16):13879-13890.
PMID: 39096311
While the urotensinergic system plays a role in influencing various pathologies, its potential remains untapped because of the absence of therapeutically effective urotensin II receptor (UTR) modulators. Herein, we developed...
4.
Tedeschi V, Sapienza S, Ciancio R, Canzoniero L, Pannaccione A, Secondo A
Curr Neuropharmacol
. 2024 May;
PMID: 38766825
Besides controlling several organellar functions, lysosomal channels also guide the catabolic "self-eating" process named autophagy, which is mainly involved in protein and organelle quality control. Neuronal cells are particularly sensitive...
5.
Cantone A, Burgaletto C, Di Benedetto G, Pannaccione A, Secondo A, Bellanca C, et al.
Cells
. 2024 Feb;
13(4.
PMID: 38391922
Alzheimer's disease (AD), marked by cognitive impairment, predominantly affects the brain regions regulated by cholinergic innervation, such as the cerebral cortex and hippocampus. Cholinergic dysfunction, a key contributor to age-related...
6.
Sapienza S, Tedeschi V, Apicella B, Pannaccione A, Russo C, Sisalli M, et al.
Ecotoxicol Environ Saf
. 2024 Feb;
273:116104.
PMID: 38377779
Increased risk of neurodegenerative diseases has been envisaged for air pollution exposure. On the other hand, environmental risk factors, including air pollution, have been suggested for Amyotrophic Lateral Sclerosis (ALS)...
7.
Piccialli I, Greco F, Roviello G, Sisalli M, Tedeschi V, Di Mola A, et al.
Biomed Pharmacother
. 2023 Oct;
168:115745.
PMID: 37871561
Amyloid β 1-42 (Aβ) protein aggregation is considered one of the main triggers of Alzheimer's disease (AD). In this study, we examined the in vitro anti-amyloidogenic activity of the isoindolinone...
8.
Sapienza S, Tedeschi V, Apicella B, Palestra F, Russo C, Piccialli I, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361823
Background: An emerging body of evidence indicates an association between anthropogenic particulate matter (PM) and neurodegeneration. Although the historical focus of PM toxicity has been on the cardiopulmonary system, ultrafine...
9.
Piccialli I, Sisalli M, de Rosa V, Boscia F, Tedeschi V, Secondo A, et al.
Cells
. 2022 Sep;
11(18).
PMID: 36139395
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions. Cortical and hippocampal hyperexcitability intervenes in the pathological derangement of brain activity leading to cognitive...
10.
Casamassa A, Cuomo O, Pannaccione A, Cepparulo P, Laudati G, Valsecchi V, et al.
Cell Calcium
. 2022 Jun;
105:102608.
PMID: 35667322
The intricate glia interaction occurring after stroke strongly depend on the maintenance of intraglial ionic homeostasis. Among the several ionic channels and transporters, the plasmamembrane Na/Ca exchanger (NCX) represents a...