Igor S A Felippe
Overview
Explore the profile of Igor S A Felippe including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
34
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Recent Articles
1.
Felippe I, Del Rio R, Schultz H, Machado B, Paton J
J Physiol
. 2023 Sep;
601(24):5527-5551.
PMID: 37747109
Carotid body pathophysiology is associated with many cardiovascular-respiratory-metabolic diseases. This pathophysiology reflects both hyper-sensitivity and hyper-tonicity. From both animal models and human patients, evidence indicates that amelioration of this pathophysiological...
2.
Zhang T, Thakkar P, Emans T, Fong D, Thampi S, Felippe I, et al.
Anesth Analg
. 2023 Feb;
137(2):440-450.
PMID: 36730724
Background: Intraoperative arterial hypotension (IOH) is a common side effect of general anesthesia (GA), associated with poor outcomes in ischemic stroke. While IOH is more prevalent with hypertension, it is...
3.
Felippe I, Zera T, da Silva M, Moraes D, McBryde F, Paton J
Cardiovasc Res
. 2022 Jan;
119(1):316-331.
PMID: 35048948
Aims: The carotid bodies (CBs) of spontaneously hypertensive (SH) rats exhibit hypertonicity and hyperreflexia contributing to heightened peripheral sympathetic outflow. We hypothesized that CB hyperexcitability is driven by its own...
4.
Felippe I, Muller C, Passamani L, Abdala A, Paton J, Sampaio K
Toxicol Appl Pharmacol
. 2022 Jan;
436:115862.
PMID: 34998853
While a considerable body of literature has characterized the clinical features induced by organophosphate pesticides, the field lacks scrutiny into cardio-respiratory changes in different phases of poisoning. Herein, we evaluated...
5.
Brognara F, Felippe I, Salgado H, Paton J
Cardiovasc Res
. 2020 Aug;
117(4):1015-1032.
PMID: 32832979
The motivation for this review comes from the emerging complexity of the autonomic innervation of the carotid body (CB) and its putative role in regulating chemoreceptor sensitivity. With the carotid...
6.
Cunha A, Felippe I, Ferreira-Junior N, Resstel L, Guimaraes D, Beijamini V, et al.
Toxicology
. 2018 Feb;
398-399:13-22.
PMID: 29471072
Although it is well-established that severe poisoning by organophosphorus (OP) compounds strongly affects the cardiorespiratory system, the effects of sub-lethal exposure to these compounds on the neural control of cardiovascular...