Ignacio Rubio
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Explore the profile of Ignacio Rubio including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
1195
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Recent Articles
1.
Wright S, Kumari P, Fraile-Agreda V, Wang C, Shivcharan S, Kappelhoff S, et al.
Cell
. 2025 Jan;
188(2):280-291.e17.
PMID: 39742811
Pyroptosis mediated by gasdermins (GSDMs) plays crucial roles in infection and inflammation. Pyroptosis triggers the release of inflammatory molecules, including damage-associated molecular patterns (DAMPs). However, the consequences of pyroptosis-especially beyond...
2.
Hussain I, Sureshkumar H, Bauer M, Rubio I
Cells
. 2024 Sep;
13(18).
PMID: 39329780
In the original publication [...].
3.
von Loeffelholz C, Winkler R, Weigel C, Piskor E, Vivas W, Rauchfuss F, et al.
iScience
. 2024 Jul;
27(7):110133.
PMID: 38984201
Sepsis is a life-threatening condition caused by dysregulated host responses to infection. Myeloid cell accumulation and lymphocyte decline are widely recognized phenomena in septic patients. However, the fate of specific...
4.
Rooney M, Duduskar S, Ghait M, Reissing J, Stengel S, Reuken P, et al.
J Hepatol
. 2024 Jun;
81(6):971-982.
PMID: 38936554
Background & Aims: Gut bacterial translocation contributes to immune dysfunction and spontaneous bacterial peritonitis (SBP) in cirrhosis. We hypothesized that exposure of peritoneal macrophages (PMs) to bacterial DNA results in...
5.
Mantecon R, Valverde-Marcos B, Rubio I, Youssef G, Loya J, Diaz-Alvarez J, et al.
Polymers (Basel)
. 2024 Jun;
16(12).
PMID: 38932102
Head impacts are a major concern in contact sports and sports with high-speed mobility due to the prevalence of head trauma events and their dire consequences. Surrogates of human heads...
6.
De Biasi S, Lo Tartaro D, Neroni A, Rau M, Paschalidis N, Borella R, et al.
Nat Commun
. 2024 Mar;
15(1):2752.
PMID: 38553477
Disease-modifying therapies (DMT) administered to patients with multiple sclerosis (MS) can influence immune responses to SARS-CoV-2 and vaccine efficacy. However, data on the detailed phenotypic, functional and metabolic characteristics of...
7.
Santacroce E, DAngerio M, Ciobanu A, Masini L, Lo Tartaro D, Coloretti I, et al.
Cells
. 2024 Mar;
13(5.
PMID: 38474403
Sepsis, a critical condition marked by systemic inflammation, profoundly impacts both innate and adaptive immunity, often resulting in lymphopenia. This immune alteration can spare regulatory T cells (Tregs) but significantly...
8.
Eberhardt N, Santamarina B, Enghardt M, Rohland O, Hussain I, Tannert A, et al.
Int J Antimicrob Agents
. 2024 Jan;
63(4):107086.
PMID: 38218325
Objectives: This study examined the potential of a novel photoactivatable ciprofloxacin to act against bacterial infections and microbiomes related to biliary diseases. It also evaluated treatment by combining the impact...
9.
Cajander S, Kox M, Scicluna B, Weigand M, Mora R, Flohe S, et al.
Lancet Respir Med
. 2023 Dec;
12(4):305-322.
PMID: 38142698
Sepsis is characterised by a dysregulated host immune response to infection. Despite recognition of its significance, immune status monitoring is not implemented in clinical practice due in part to the...
10.
Husain R, Jiao X, Hennings J, Giesecke J, Palsule G, Beck-Wodl S, et al.
Brain
. 2023 Dec;
147(4):1197-1205.
PMID: 38141063
Dysfunctional RNA processing caused by genetic defects in RNA processing enzymes has a profound impact on the nervous system, resulting in neurodevelopmental conditions. We characterized a recessive neurological disorder in...