Ignacio Rubio
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Explore the profile of Ignacio Rubio including associated specialties, affiliations and a list of published articles.
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69
Citations
1195
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Recent Articles
11.
Ghait M, Duduskar S, Rooney M, Hafner N, Reng L, Gohrig B, et al.
Front Immunol
. 2023 Dec;
14:1239474.
PMID: 38106412
The non-canonical inflammasome, which includes caspase-11 in mice and caspase-4 and caspase-5 in humans, is upregulated during inflammatory processes and activated in response to bacterial infections to carry out pyroptosis....
12.
Kumari P, Vasudevan S, Russo A, Wright S, Fraile-Agreda V, Krajewski D, et al.
Nat Cell Biol
. 2023 Nov;
25(12):1860-1872.
PMID: 37973841
Intracellular surveillance for systemic microbial components during homeostasis and infections governs host physiology and immunity. However, a long-standing question is how circulating microbial ligands become accessible to intracellular receptors. Here...
13.
Diaz-Alvarez A, Rodriguez-Millan M, Rubio I, Kim D, Diaz-Alvarez J
Polymers (Basel)
. 2023 Oct;
15(19).
PMID: 37835931
Ultrahigh-molecular-weight polyethylene (UHMWPE) is used in the defence industry mainly owing to its properties, such as excellent dimensional stability, excellent ballistic performance, and light weight. Although UHMWPE laminates are generally...
14.
Leonhardt J, Dorresteijn M, Neugebauer S, Mihaylov D, Kunze J, Rubio I, et al.
Crit Care
. 2023 Sep;
27(1):372.
PMID: 37759239
Background: Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying mechanisms is needed to develop targeted therapies. Circulating...
15.
Osadare I, Xiong L, Rubio I, Neugebauer U, Press A, Ramoji A, et al.
Int J Mol Sci
. 2023 Aug;
24(15).
PMID: 37569403
Sepsis is a life-threatening condition that results from an overwhelming and disproportionate host response to an infection. Currently, the quality and extent of the immune response are evaluated based on...
16.
Hussain I, Sureshkumar H, Bauer M, Rubio I
Cells
. 2023 Jun;
12(12).
PMID: 37371138
Methods: We have used an immortalized hepatocyte line as a model of the liver parenchyma to uncover the role of caloric restriction in the resilience of hepatocytes to inflammatory cell...
17.
Garloff V, Kruger T, Brakhage A, Rubio I
J Proteomics
. 2023 Mar;
279:104886.
PMID: 36966971
Proximity biotinylation screens are a widely used strategy for the unbiased identification of interacting or vicinal proteins. The latest generation biotin ligase TurboID has broadened the range of potential applications,...
18.
Naumann M, Arend N, Guliev R, Kretzer C, Rubio I, Werz O, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614272
Macrophages are important cells of the innate immune system that play many different roles in host defense, a fact that is reflected by their polarization into many distinct subtypes. Depending...
19.
Ghait M, Husain R, Duduskar S, Haack T, Rooney M, Gohrig B, et al.
Eur J Immunol
. 2022 Mar;
52(6):907-923.
PMID: 35334124
TLRs mediate the recognition of microbial and endogenous insults to orchestrate the inflammatory response. TLRs localize to the plasma membrane or endomembranes, depending on the member, and rely critically on...
20.
Baker M, Rubio I
Methods Mol Biol
. 2021 May;
2262:117-135.
PMID: 33977474
Ras and its related small GTPases are important signalling nodes that regulate a wide variety of cellular functions. The active form of these proteins exists in a transient GTP bound...