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Ignacio Rodriguez-Crespo

Explore the profile of Ignacio Rodriguez-Crespo including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 854
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Recent Articles
1.
Maroto I, Costas-Insua C, Montero-Fernandez C, Hermoso-Lopez A, Lebouc M, Bajo-Graneras R, et al.
J Neurosci . 2024 Aug; 44(39). PMID: 39168654
Growth-associated protein of 43 kDa (GAP43) is a key cytoskeleton-associated component of the presynaptic terminal that facilitates neuroplasticity. Downregulation of GAP43 expression has been associated to various psychiatric conditions in...
2.
Costas-Insua C, Hermoso-Lopez A, Moreno E, Montero-Fernandez C, Alvaro-Blazquez A, Maroto I, et al.
EMBO Mol Med . 2024 Mar; 16(4):755-783. PMID: 38514794
Cereblon/CRBN is a substrate-recognition component of the Cullin4A-DDB1-Roc1 E3 ubiquitin ligase complex. Destabilizing mutations in the human CRBN gene cause a form of autosomal recessive non-syndromic intellectual disability (ARNSID) that...
3.
Maroto I, Moreno E, Costas-Insua C, Merino-Gracia J, Diez-Alarcia R, Alvaro-Blazquez A, et al.
Neuropharmacology . 2023 Sep; 240:109712. PMID: 37689260
Cannabinoids exert pleiotropic effects on the brain by engaging the cannabinoid CB receptor (CBR), a presynaptic metabotropic receptor that regulates key neuronal functions in a highly context-dependent manner. We have...
4.
Maroto I, Costas-Insua C, Berthoux C, Moreno E, Ruiz-Calvo A, Montero-Fernandez C, et al.
Nat Commun . 2023 Apr; 14(1):2303. PMID: 37085487
The type-1 cannabinoid receptor (CBR) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction...
5.
Gomez-Almeria M, Burgaz S, Costas-Insua C, Rodriguez-Cueto C, Santos-Garcia I, Rodriguez-Crespo I, et al.
Int J Mol Sci . 2021 Nov; 22(22). PMID: 34830414
In the present study, we investigated the involvement of the chaperone protein BiP (also known as GRP78 or Hspa5), a master regulator of intracellular proteostasis, in two mouse models of...
6.
Costas-Insua C, Moreno E, Maroto I, Ruiz-Calvo A, Bajo-Graneras R, Martin-Gutierrez D, et al.
J Neurosci . 2021 Aug; 41(38):7924-7941. PMID: 34353897
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CBR). Accruing evidence supports that cannabinoid action relies on...
7.
Illescas B, Perez-Sanchez A, Mallo A, Martin-Domenech A, Rodriguez-Crespo I, Martin N
J Mater Chem B . 2020 May; 8(20):4505-4515. PMID: 32369088
Non-viral nucleic acid vectors able to display high transfection efficiencies with low toxicity and overcoming the multiple biological barriers are needed to further develop the clinical applications of gene therapy....
8.
Aicart-Ramos C, Sanchez-Ruiloba L, Gomez-Parrizas M, Zaragoza C, Iglesias T, Rodriguez-Crespo I
J Cell Sci . 2018 Jun; 131(10). PMID: 29866765
No abstract available.
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Navarro-Lerida I, Portoles M, Alvarez Barrientos A, Gavilanes F, Bosca L, Rodriguez-Crespo I
J Cell Sci . 2018 Jun; 131(10). PMID: 29866763
No abstract available.