Ian Q Weigle
Overview
Explore the profile of Ian Q Weigle including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
79
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Recent Articles
1.
Bosch M, Dodiya H, Michalkiewicz J, Lee C, Shaik S, Weigle I, et al.
Mol Neurodegener
. 2024 Oct;
19(1):70.
PMID: 39390529
No abstract available.
2.
Bosch M, Dodiya H, Michalkiewicz J, Lee C, Shaik S, Weigle I, et al.
Mol Neurodegener
. 2024 Feb;
19(1):18.
PMID: 38365827
It has recently become well-established that there is a connection between Alzheimer's disease pathology and gut microbiome dysbiosis. We have previously demonstrated that antibiotic-mediated gut microbiota perturbations lead to attenuation...
3.
Saha P, Weigle I, Slimmon N, Poli P, Patel P, Zhang X, et al.
Sci Rep
. 2024 Jan;
14(1):1827.
PMID: 38246956
It is well-established that women are disproportionately affected by Alzheimer's disease. The mechanisms underlying this sex-specific disparity are not fully understood, but several factors that are often associated-including interactions of...
4.
Chandra S, Di Meco A, Dodiya H, Popovic J, Cuddy L, Weigle I, et al.
Mol Neurodegener
. 2023 Jul;
18(1):45.
PMID: 37415149
Background: Previous studies show that antibiotic-mediated (abx) alteration of the gut microbiome (GMB) results in a reduction of amyloid beta (Aβ) plaques and proinflammatory microglial phenotype in male APPPS1-21 mice....
5.
Dodiya H, Lutz H, Weigle I, Patel P, Michalkiewicz J, Roman-Santiago C, et al.
J Exp Med
. 2021 Dec;
219(1).
PMID: 34854884
We previously demonstrated that lifelong antibiotic (ABX) perturbations of the gut microbiome in male APPPS1-21 mice lead to reductions in amyloid β (Aβ) plaque pathology and altered phenotypes of plaque-associated...
6.
Zhang X, Zhang C, Prokopenko D, Liang Y, Zhen S, Weigle I, et al.
J Exp Med
. 2021 Apr;
218(6).
PMID: 33822840
Familial Alzheimer's disease (FAD)-linked mutations in the APP gene occur either within the Aβ-coding region or immediately proximal and are located in exons 16 and 17, which encode Aβ peptides....