Ian Croy
Overview
Explore the profile of Ian Croy including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
128
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0
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Recent Articles
1.
Hollis R, Churchman M, Grimes G, Meynert A, Gautier P, McMahon L, et al.
Eur J Cancer
. 2025 Feb;
219:115299.
PMID: 39955805
Background: Half of high grade serous tubo-ovarian carcinomas (HGSOC) demonstrate homologous recombination repair (HRR) deficiency, most commonly through germline or somatic pathogenic variants in BRCA1/2 (gBRCA1/2 or sBRCA1/2). gBRCA1/2 is...
2.
Southworth E, Thomson J, Croy I, Churchman M, Arends M, Hollis R, et al.
Eur J Cancer
. 2024 Jul;
208:114205.
PMID: 38986422
Introduction: Concurrent non-serous endometrial and ovarian tumours are often managed clinically as two separate primary tumours, but almost all exhibit evidence of a genomic relationship. Methodology: This study investigates the...
3.
Herrington C, Oswald A, Stillie L, Croy I, Churchman M, Hollis R
Br J Cancer
. 2023 Dec;
130(2):327-335.
PMID: 38097740
Background: Ovarian carcinosarcoma (OCS) is an exceptionally aggressive and understudied ovarian cancer type harbouring distinct carcinomatous and sarcomatous compartments. Here, we seek to identify shared and compartment-specific events that may...
4.
Thomson J, Hollis R, van Baal J, Ilenkovan N, Churchman M, Van de Vijver K, et al.
Gynecol Oncol
. 2023 May;
174:157-166.
PMID: 37207500
Objectives: Low-grade serous ovarian carcinoma (LGSOC) is a distinct, rare, ovarian cancer type characterised by younger patient age and intrinsic chemoresistance. Understanding the molecular landscape is crucial for optimising targeted...
5.
Hollis R, Thomson J, van Baal J, Ilenkovan N, Churchman M, Van de Vijver K, et al.
Sci Rep
. 2023 May;
13(1):7681.
PMID: 37169775
Low grade serous ovarian carcinoma (LGSOC) demonstrates unique clinical and molecular features compared to other ovarian cancer types. The relationship between common histological features of LGSOC and molecular events, such...
6.
Hollis R, Croy I, Churchman M, Bartos C, Rye T, Gourley C, et al.
Br J Cancer
. 2022 Jun;
127(6):1034-1042.
PMID: 35715633
Background: Ovarian carcinosarcoma (OCS) is an uncommon, biphasic and highly aggressive ovarian cancer type, which has received relatively little research attention. Methods: We curated the largest pathologically confirmed OCS cohort...
7.
Hollis R, Meynert A, Michie C, Rye T, Churchman M, Hallas-Potts A, et al.
Clin Cancer Res
. 2022 Jun;
28(16):3546-3556.
PMID: 35696721
Purpose: High-grade serous ovarian carcinoma (HGSOC) is the most common ovarian cancer type; most patients experience disease recurrence that accumulates chemoresistance, leading to treatment failure. Genomic and transcriptomic features have...
8.
Hollis R, Stanley B, Thomson J, Churchman M, Croy I, Rye T, et al.
NPJ Precis Oncol
. 2021 Jun;
5(1):47.
PMID: 34079052
Endometrioid ovarian carcinoma (EnOC) is an under-investigated ovarian cancer type. Recent studies have described disease subtypes defined by genomics and hormone receptor expression patterns; here, we determine the relationship between...
9.
Ewing A, Meynert A, Churchman M, Grimes G, Hollis R, Herrington C, et al.
Clin Cancer Res
. 2021 Mar;
27(11):3201-3214.
PMID: 33741650
Purpose: The abundance and effects of structural variation at BRCA1/2 in tumors are not well understood. In particular, the impact of these events on homologous recombination repair deficiency (HRD) has...
10.
Hollis R, Thomson J, Stanley B, Churchman M, Meynert A, Rye T, et al.
Nat Commun
. 2020 Oct;
11(1):4995.
PMID: 33020491
Endometrioid ovarian carcinoma (EnOC) demonstrates substantial clinical and molecular heterogeneity. Here, we report whole exome sequencing of 112 EnOC cases following rigorous pathological assessment. We detect a high frequency of...