Ian A Nicastro
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Explore the profile of Ian A Nicastro including associated specialties, affiliations and a list of published articles.
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4
Citations
32
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Recent Articles
1.
Schiksnis E, Nicastro I, Pasquinelli A
Nucleic Acids Res
. 2024 Nov;
52(22):13896-13913.
PMID: 39558169
Organismal aging is marked by decline in cellular function and anatomy, ultimately resulting in death. To inform our understanding of the mechanisms underlying this degeneration, we performed standard RNA sequencing...
2.
Schiksnis E, Nicastro I, Pasquinelli A
bioRxiv
. 2024 Jul;
PMID: 38948813
Organismal aging is marked by decline in cellular function and anatomy, ultimately resulting in death. To inform our understanding of the mechanisms underlying this degeneration, we performed standard RNA sequencing...
3.
Chipman L, Luc S, Nicastro I, Hulahan J, Dann D, Bodas D, et al.
PLoS Genet
. 2023 Nov;
19(11):e1011055.
PMID: 38011256
MicroRNAs (miRNAs) regulate gene expression by base-pairing to target sequences in messenger RNAs (mRNAs) and recruiting factors that induce translational repression and mRNA decay. In animals, nucleotides 2-8 at the...
4.
Aalto A, Nicastro I, Broughton J, Chipman L, Schreiner W, Chen J, et al.
PLoS Genet
. 2018 Jun;
14(6):e1007379.
PMID: 29927939
Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the...