Iain M Robinson
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Explore the profile of Iain M Robinson including associated specialties, affiliations and a list of published articles.
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13
Citations
740
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Recent Articles
1.
Burr S, Gale T, Kisielewska J, Millin P, Pego J, Pinter G, et al.
MedEdPublish (2016)
. 2023 Nov;
13:221.
PMID: 38028657
Adaptive testing has a long but largely unrecognized history. The advent of computer-based testing has created new opportunities to incorporate adaptive testing into conventional programmes of study. Relatively recently software...
2.
Bohme M, Beis C, Reddy-Alla S, Reynolds E, Mampell M, Grasskamp A, et al.
Nat Neurosci
. 2016 Aug;
19(10):1311-20.
PMID: 27526206
Brain function relies on fast and precisely timed synaptic vesicle (SV) release at active zones (AZs). Efficacy of SV release depends on distance from SV to Ca(2+) channel, but molecular...
3.
Wishart T, Mutsaers C, Riessland M, Reimer M, Hunter G, Hannam M, et al.
J Clin Invest
. 2014 Mar;
124(4):1821-34.
PMID: 24590288
The autosomal recessive neurodegenerative disease spinal muscular atrophy (SMA) results from low levels of survival motor neuron (SMN) protein; however, it is unclear how reduced SMN promotes SMA development. Here,...
4.
Sutcliffe B, Forero M, Zhu B, Robinson I, Hidalgo A
PLoS One
. 2013 Oct;
8(10):e75902.
PMID: 24124519
Retrograde growth factors regulating synaptic plasticity at the neuromuscular junction (NMJ) in Drosophila have long been predicted but their discovery has been scarce. In vertebrates, such retrograde factors produced by...
5.
Takeda T, Robinson I, Savoian M, Griffiths J, Whetton A, McMahon H, et al.
Open Biol
. 2013 Aug;
3(8):130081.
PMID: 23926047
Cytokinesis is a highly ordered cellular process driven by interactions between central spindle microtubules and the actomyosin contractile ring linked to the dynamic remodelling of the plasma membrane. The mechanisms...
6.
Diaper D, Adachi Y, Sutcliffe B, Humphrey D, Elliott C, Stepto A, et al.
Hum Mol Genet
. 2013 Jan;
22(8):1539-57.
PMID: 23307927
Cytoplasmic accumulation and nuclear clearance of TDP-43 characterize familial and sporadic forms of amyotrophic lateral sclerosis and frontotemporal lobar degeneration, suggesting that either loss or gain of TDP-43 function, or...
7.
Milton V, Jarrett H, Gowers K, Chalak S, Briggs L, Robinson I, et al.
Proc Natl Acad Sci U S A
. 2011 Oct;
108(42):17521-6.
PMID: 21987827
Synaptic terminals are known to expand and contract throughout an animal's life. The physiological constraints and demands that regulate appropriate synaptic growth and connectivity are currently poorly understood. In previous...
8.
Rocha J, Korolchuk V, Robinson I, OKane C
PLoS One
. 2011 May;
6(4):e19087.
PMID: 21559499
RNA interference (RNAi) has a range of physiological functions including as a defence mechanism against viruses. To protect uninfected cells in a multicellular organism, not only a cell-autonomous RNAi response...
9.
Morse R, Todd A, Shaw D, McConville A, Robinson I, Young P
Neuromolecular Med
. 2010 Nov;
13(1):77-87.
PMID: 21082361
The childhood disorder spinal muscular atrophy (SMA) is caused by reduced expression of the survival motor neuron (SMN) protein. SMN is a multifunctional protein that has been implicated in the...
10.
Korolchuk V, Schutz M, Gomez-Llorente C, Rocha J, Lansu N, Collins S, et al.
J Cell Sci
. 2007 Dec;
120(Pt 24):4367-76.
PMID: 18057029
To identify novel proteins required for receptor-mediated endocytosis, we have developed an RNAi-based screening method in Drosophila S2 cells, based on uptake of a scavenger receptor ligand. Some known endocytic...