I S Krishnan
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Explore the profile of I S Krishnan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
13
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Recent Articles
1.
Sreedharan S, Krishnan I
J Indian Soc Pedod Prev Dent
. 2012 Dec;
30(3):275-8.
PMID: 23263436
Odontomas are considered to be the most common odontogenic tumors of the oral cavity. Some authors consider it as malformations rather than true neoplasms. The exact etiology of odontomes is...
2.
Losman M, Qu Z, Krishnan I, Wang J, Hansen H, Goldenberg D, et al.
Clin Cancer Res
. 1999 Nov;
5(10 Suppl):3101s-3105s.
PMID: 10541350
Antibody humanization has eliminated or reduced the human antimouse antibody response associated with the administration of murine antibodies. We have successfully humanized three different antibodies: (a) hMN-3 (granulocyte targeting); (b)...
3.
Krishnan I, Hansen H, Gold D, Goldenberg D, Leung S
Hybridoma
. 1999 Nov;
18(4):325-33.
PMID: 10571262
Mu-9 is a monoclonal antibody (MAb) specific for the CSAp antigen (Ag) expressed by colorectal cancers. By using variable (V)-region-specific primers, the respective VH and VL sequences of Mu-9 were...
4.
Chimerization of Mu-9: a colon-specific antigen-p antibody reactive with gastrointestinal carcinomas
Krishnan I, Hansen H, Losman M, Goldenberg D, Leung S
Cancer
. 1997 Dec;
80(12 Suppl):2667-74.
PMID: 9406723
Background: Mu-9 is a murine monoclonal antibody that is directed against affinity-purified colon-specific antigen-p (CSAp). CSAp is a tumor-associated antigen that is present in 60% of colorectal carcinomas. Preclinical and...
5.
Losman M, Hansen H, Dworak H, Krishnan I, Qu Z, Shih L, et al.
Cancer
. 1997 Dec;
80(12 Suppl):2660-6.
PMID: 9406722
Background: LL2 is a murine immunoglobulin (Ig)G2a-kappa anti-B-cell monoclonal antibody with proven targeting and therapeutic efficacy in the management of non-Hodgkin's lymphoma (NHL). The authors had previously generated a humanized...
6.
Krishnan I, Kovacs E, Sass P
FEBS Lett
. 1994 Oct;
353(2):185-8.
PMID: 7523193
Site directed mutagenesis/charged-to-alanine scanning mutagenesis of the amino terminal portion of human ERK2 (from amino acids 1 to 150) purified as a glutathione-S-transferase fusion protein (GST-ERK2) from E. coli has...
7.
Singhal R, Krishnan I, Dua R
Biochemistry
. 1989 Sep;
28(19):7928-35.
PMID: 2611221
Clostridium pasteurianum possesses a high level of glutamate synthase (EC 1.4.1.14) activity and cell yield when grown on 4 mM ammonium chloride and molasses as the sole nitrogen and carbon...
8.
Krishnan I, Singhal R, Dua R
Biochemistry
. 1986 Apr;
25(7):1589-99.
PMID: 2871863
Glutamine synthetase from Clostridium pasteurianum grown on molasses as the sole carbon source and ammonium chloride as the nitrogen source has been purified to homogeneity (45-fold) with 32% recovery. The...
9.
Krishnan I, Dua R
FEBS Lett
. 1985 Jun;
185(2):267-71.
PMID: 2860014
Preliminary chemical modification studies indicated the presence of tyrosine, carboxyl, arginine, histidine and the absence of serine and sulfhydryl residues at or near the active site of Clostridium pasteurianum glutamine...