I P Whitehead
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Explore the profile of I P Whitehead including associated specialties, affiliations and a list of published articles.
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20
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720
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Recent Articles
1.
Pannucci N, Li D, Sahay S, Thomas E, Chen R, Tala I, et al.
Blood Cancer J
. 2013 Aug;
3:e135.
PMID: 23955590
Previous studies have demonstrated that p210 BCR/ABL1 interacts directly with the xeroderma pigmentosum group B (XPB) protein, and that XPB is phosphorylated on tyrosine in cells that express p210 BCR/ABL1....
2.
Tala I, Chen R, Hu T, Fitzpatrick E, Williams D, Whitehead I
Leukemia
. 2012 Dec;
27(5):1080-9.
PMID: 23207522
We have previously identified a tyrosine kinase-independent, guanine nucleotide exchange factor (GEF) activity, which is contained within the region of p210 no expansion BCR/ABL that distinguishes it from p190 BCR/ABL....
3.
Sahay S, Pannucci N, Mahon G, Rodriguez P, Megjugorac N, Kostenko E, et al.
Oncogene
. 2007 Oct;
27(14):2064-71.
PMID: 17922031
The BCR-ABL oncogene encodes an in-frame fusion protein containing N-terminal sequences derived from Bcr and C-terminal sequences derived from Abl. Bcr contains a centrally located Rho-specific guanine nucleotide exchange factor...
4.
The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
Martin C, Mahon G, Klinger M, Kay R, Symons M, Der C, et al.
Oncogene
. 2001 May;
20(16):1953-63.
PMID: 11360179
We utilized a cDNA expression library derived from the B6SutA(1) mouse myeloid progenitor cell line to search for novel oncogenes that promote growth transformation of NIH3T3 cells. A 2.2 kb...
5.
Whitehead I, Zohn I, Der C
Oncogene
. 2001 Apr;
20(13):1547-55.
PMID: 11313901
G protein coupled receptors (GPCRs) constitute the largest family of cell surface receptors, with more than 1000 members, and are responsible for converting a diverse array of extracellular stimuli into...
6.
7.
Zhang H, Wang L, Kao S, Whitehead I, Hart M, Liu B, et al.
Curr Biol
. 1999 Nov;
9(21):1271-4.
PMID: 10556093
The long cytoplasmic tail of the human immunodeficiency virus (HIV)-1 transmembrane protein gp41 (gp41C) is implicated in the replication and cytopathicity of HIV-1 [1]. Little is known about the specific...
8.
Whitehead I, Lambert Q, Glaven J, Abe K, Rossman K, Mahon G, et al.
Mol Cell Biol
. 1999 Oct;
19(11):7759-70.
PMID: 10523665
Dbs was identified initially as a transforming protein and is a member of the Dbl family of proteins (>20 mammalian members). Here we show that Dbs, like its rat homolog...
9.
Abe K, Whitehead I, OBryan J, Der C
J Biol Chem
. 1999 Oct;
274(43):30410-8.
PMID: 10521418
Deletion of the NH(2)-terminal 65 amino acids of proto-Vav (to form onco-Vav) activates its transforming activity, suggesting that these sequences serve a negative regulatory role in Vav function. However, the...
10.
Tognon C, Kirk H, Passmore L, Whitehead I, Der C, Kay R
Mol Cell Biol
. 1998 Nov;
18(12):6995-7008.
PMID: 9819387
As part of a cDNA library screen for clones that induce transformation of NIH 3T3 fibroblasts, we have isolated a cDNA encoding the murine homolog of the guanine nucleotide exchange...