I P Kirk
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Explore the profile of I P Kirk including associated specialties, affiliations and a list of published articles.
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7
Citations
106
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Recent Articles
1.
Jin J, Tomlinson W, Kirk I, Kim Y, Humphries R, Kunapuli S
Br J Pharmacol
. 2001 Jun;
133(4):521-8.
PMID: 11399669
P2Y receptor activation in many cell types leads to phospholipase C activation and accumulation of inositol phosphates, while in blood platelets, C6-2B glioma cells, and in B10 microvascular endothelial cells...
2.
Fagura M, Dainty I, McKay G, Kirk I, Humphries R, Robertson M, et al.
Br J Pharmacol
. 1998 Jun;
124(1):157-64.
PMID: 9630355
1. In the present study we have classified the receptor(s) mediating increases in intracellular calcium concentration ([Ca2+]i) in human washed platelets and compared the pharmacological profile obtained with that observed...
3.
Kirk I, Richardson P
J Neurochem
. 1995 Jun;
64(6):2801-9.
PMID: 7760061
The adenosine A2a receptor inhibition of potassium (15 mM)-evoked GABA release from striatal nerve terminals has been examined. High extracellular calcium concentrations (4 mM) reduced the effect of the A2a...
4.
Kirk I, Richardson P
Br J Pharmacol
. 1995 Jan;
114(2):537-43.
PMID: 7881753
1. The putative high affinity binding site for the adenosine A2A receptor agonist 2-p-(2-carboxyethyl)phenethyl-amino-5'-N- ethylcarboxamidoadenosine (CGS 21680) in the rat cerebral cortex was characterized by use of a number of...
5.
Inhibition by KF17837 of adenosine A2A receptor-mediated modulation of striatal GABA and ACh release
Kurokawa M, Kirk I, Kirkpatrick K, Kase H, Richardson P
Br J Pharmacol
. 1994 Sep;
113(1):43-8.
PMID: 7812630
1. The effect of the A2A adenosine receptor agonist, 2-p-(2-carboxyethyl)phenethyl-amino-5'-N-ethylcarboxamidoadenosine (CGS 21680) on the potassium evoked release of [3H]-gamma-aminobutyric acid ([3H]-GABA) from nerve terminals derived from the caudate-putamen and the...
6.
Kirk I, Richardson P
J Neurochem
. 1994 Mar;
62(3):960-6.
PMID: 8113816
The ability of adenosine agonists to modulate K(+)-evoked gamma-[3H]aminobutyric acid ([3H]GABA) and acetylcholine (ACh) release from rat striatal synaptosomes was investigated. The A2a receptor-selective agonist CGS 21680 inhibited Ca(2+)-dependent [3H]GABA...
7.
Beresford A, Caswell K, Chambers R, Kirk I
Xenobiotica
. 1992 Jul;
22(7):789-98.
PMID: 1360732
1. Achiral reverse-phase h.p.l.c. with semi-automated post-column fraction collection and solid-phase sample reconcentration, has been applied as the purification procedure during the enantiomeric quantification of two widely differing experimental drugs;...