Hyejung Won
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Explore the profile of Hyejung Won including associated specialties, affiliations and a list of published articles.
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8036
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Recent Articles
1.
Liu R, Zhang Z, Won H, Marron J
Bioinformatics
. 2025 Mar;
41(3).
PMID: 40036585
Motivation: Hi-C technology has been developed to profile genome-wide chromosome conformation. So far Hi-C data have been generated from a large compendium of different cell types and different tissue types....
2.
Matoba N, McAfee J, Krupa O, Bell J, Le B, Valone J, et al.
bioRxiv
. 2025 Feb;
PMID: 39974944
Genetic association studies have identified hundreds of largely non-coding loci associated with inter-individual differences in the structure of the human cortex, though the specific genetic variants that impact regulatory activity...
3.
Lee S, McAfee J, Lee J, Gomez A, Ledford A, Clarke D, et al.
Cell
. 2025 Jan;
188(5):1409-1424.e21.
PMID: 39848247
A meta-genome-wide association study across eight psychiatric disorders has highlighted the genetic architecture of pleiotropy in major psychiatric disorders. However, mechanisms underlying pleiotropic effects of the associated variants remain to...
4.
Degner K, Bell J, Jones S, Won H
Cell Insight
. 2024 Dec;
4(1):100214.
PMID: 39618480
The human genome is largely noncoding, yet the field is still grasping to understand how noncoding variants impact transcription and contribute to disease etiology. The massively parallel reporter assay (MPRA)...
5.
Bond M, Quiroga-Barber I, DCosta S, Wu Y, Bell J, McAfee J, et al.
medRxiv
. 2024 Oct;
PMID: 39371155
Genome-wide association studies have identified loci associated with Alzheimer's Disease (AD), but identifying the exact causal variants and genes at each locus is challenging due to linkage disequilibrium and their...
6.
Levin M, Huffman J, Verma A, Sullivan K, Rodriguez A, Kainer D, et al.
Nat Cardiovasc Res
. 2024 Aug;
2(1):44-57.
PMID: 39196206
Varicose veins represent a common cause of cardiovascular morbidity, with limited available medical therapies. Although varicose veins are heritable and epidemiologic studies have identified several candidate varicose vein risk factors,...
7.
Carnes M, Quach B, Zhou L, Han S, Tao R, Mandal M, et al.
Neuropsychopharmacology
. 2024 Jun;
49(11):1749-1757.
PMID: 38830989
Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWASs) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants...
8.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
Science
. 2024 May;
384(6698):eadi5199.
PMID: 38781369
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
9.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
bioRxiv
. 2024 Apr;
PMID: 38562822
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet, little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
10.
Girault J, Veatch O, Won H
J Neurodev Disord
. 2024 Mar;
16(1):8.
PMID: 38481128
No abstract available.