Hye-Sook Kwon
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Explore the profile of Hye-Sook Kwon including associated specialties, affiliations and a list of published articles.
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17
Citations
969
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Recent Articles
1.
Chang C, Bhagchandani P, Poyser J, Velasco B, Zhao W, Kwon H, et al.
Cell Rep
. 2022 Nov;
41(6):111615.
PMID: 36351397
Mixed hematopoietic chimerism can promote immune tolerance of donor-matched transplanted tissues, like pancreatic islets. However, adoption of this strategy is limited by the toxicity of standard treatments that enable donor...
2.
George B, Kao K, Kwon H, Velasco B, Poyser J, Chen A, et al.
Cell Stem Cell
. 2019 Jun;
25(2):185-192.e3.
PMID: 31204177
Hematopoietic cell transplantation can correct hematological and immunological disorders by replacing a diseased blood system with a healthy one, but this currently requires depleting a patient's existing hematopoietic system with...
3.
Kwon H, Logan A, Chhabra A, Pang W, Czechowicz A, Tate K, et al.
Blood
. 2019 Jan;
133(19):2104-2108.
PMID: 30617195
No abstract available.
4.
Jeng M, Hull P, Fei M, Kwon H, Tsou C, Kasler H, et al.
J Exp Med
. 2017 Dec;
215(1):51-62.
PMID: 29191913
The expansion of CD8CD28 T cells, a population of terminally differentiated memory T cells, is one of the most consistent immunological changes in humans during aging. CD8CD28 T cells are...
5.
Pierini A, Nishikii H, Baker J, Kimura T, Kwon H, Pan Y, et al.
Nat Commun
. 2017 May;
8:15068.
PMID: 28485401
Foxp3 regulatory T cells (Treg cells) modulate the immune system and maintain self-tolerance, but whether they affect haematopoiesis or haematopoietic stem cell (HSC)-mediated reconstitution after transplantation is unclear. Here we...
6.
Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al.
Cell
. 2017 Mar;
168(6):1041-1052.e18.
PMID: 28283060
Most secreted growth factors and cytokines are functionally pleiotropic because their receptors are expressed on diverse cell types. While important for normal mammalian physiology, pleiotropy limits the efficacy of cytokines...
7.
Chhabra A, Ring A, Weiskopf K, Schnorr P, Gordon S, Le A, et al.
Sci Transl Med
. 2016 Aug;
8(351):351ra105.
PMID: 27510901
Hematopoietic stem cell (HSC) transplantation can cure diverse diseases of the blood system, including hematologic malignancies, anemias, and autoimmune disorders. However, patients must undergo toxic conditioning regimens that use chemotherapy...
8.
Lim H, Kang S, Ryu J, Schilling B, Fei M, Lee I, et al.
J Exp Med
. 2015 May;
212(6):973.
PMID: 25987725
No abstract available.
9.
Lim H, Kang S, Ryu J, Schilling B, Fei M, Lee I, et al.
J Exp Med
. 2015 Apr;
212(5):607-17.
PMID: 25918343
The balance of effector and regulatory T cell function, dependent on multiple signals and epigenetic regulators, is critical to immune self-tolerance. Dysregulation of T helper 17 (Th17) effector cells is...
10.
Kwon H, Lim H, Wu J, Schnolzer M, Verdin E, Ott M
J Immunol
. 2012 Feb;
188(6):2712-21.
PMID: 22312127
The Foxp3 transcription factor is the master regulator of regulatory T cell (Treg) differentiation and function. Its activity is regulated by reversible acetylation. Using mass spectrometry of immunoprecipitated proteins, we...