Hui Gyu Park
Overview
Explore the profile of Hui Gyu Park including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
388
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Recent Articles
1.
Patel V, Li Y, Benhamou L, Park H, Raleigh M, Brenna J, et al.
Cancers (Basel)
. 2025 Feb;
17(3).
PMID: 39941731
: Neuroblastoma is a genetically diverse, highly metastatic pediatric cancer accounting for 15% of childhood cancer deaths despite only having ~8% of childhood cancer incidence. The current standard of care...
2.
Garza S, James G, Park H, Baker P, Brenna J
Anal Chem
. 2024 Sep;
PMID: 39279131
Highly unsaturated fatty acids (HUFAs) are vulnerable to oxygen attack, thus making HUFA-rich, high metabolic rate/reactive oxygen species (ROS)-generating neurological tissue particularly susceptible to increased oxidative stress. Lipid oxidation is...
3.
Sheeter D, Garza S, Park H, Benhamou L, Badi N, Espinosa E, et al.
Cancers (Basel)
. 2024 Apr;
16(8).
PMID: 38672672
amplification () and disruption of tumor suppressor microRNA (TSmiR) function are key drivers of poor outcomes in neuroblastoma (NB). While MYCN and TSmiRs regulate glucose metabolism, their role in de...
4.
Kothapalli K, Park H, Kothapalli N, Brenna J
Prog Lipid Res
. 2023 Aug;
92:101242.
PMID: 37597812
Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as arachidonic acid. The...
5.
James G, Stephenson K, Callaghan-Gillespie M, Kamara M, Park H, Brenna J, et al.
Foods
. 2023 Jan;
12(2).
PMID: 36673399
Ready-to-use therapeutic food (RUTF) is used to treat young children diagnosed with severe acute malnutrition. RUTF with low and balanced linoleic and alpha-linolenic acid, plus omega-3 docosahexaenoic acid (DHA), supports...
6.
Wang D, Vidovic D, McKay A, Darwish T, Park H, Garza S, et al.
Anal Chem
. 2022 Sep;
94(38):12971-12980.
PMID: 36098546
Ru-based catalysis results in highly unsaturated fatty acid (HUFA) ethyl esters (EE) deuterated to various extents. The products carry H (D) mainly at their -allylic positions, where they are resistant...
7.
James G, Bohannan W, Adewunmi E, Schmidt K, Park H, Shchepinov M, et al.
Exp Eye Res
. 2022 Jul;
222:109193.
PMID: 35870486
Docosahexaenoic acid (DHA; 22:6n-3) rich photoreceptors function in a highly oxidizing microenvironment. Lipid peroxidation and inflammation contribute to initiation and progression of eye diseases including age-related macular degeneration (AMD). Deuteration...
8.
Lee S, Benvie A, Park H, Spektor R, Harlan B, Brenna J, et al.
Commun Biol
. 2022 Jun;
5(1):584.
PMID: 35701601
Beige adipocytes are induced by cold temperatures or β3-adrenergic receptor (Adrb3) agonists. They create heat through glucose and fatty acid (FA) oxidation, conferring metabolic benefits. The distinct and shared mechanisms...
9.
Molchanova A, Rjabceva S, Melik-Kasumov T, Pestov N, Angelova P, Shmanai V, et al.
Antioxidants (Basel)
. 2022 Apr;
11(4).
PMID: 35453366
Arachidonic acid (ARA) is a major component of lipid bilayers as well as the key substrate for the eicosanoid cascades. ARA is readily oxidized, and its non-enzymatic and enzymatic oxidation...
10.
Liu Y, Bell B, Song Y, Zhang K, Anderson B, Axelsen P, et al.
Aging Cell
. 2022 Mar;
21(4):e13579.
PMID: 35257475
Oxidative stress plays a central role in age-related macular degeneration (AMD). Iron, a potent generator of hydroxyl radicals through the Fenton reaction, has been implicated in AMD. One easily oxidized...