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Hugo Poplimont

Explore the profile of Hugo Poplimont including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 105
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Recent Articles
1.
Varady A, Grissenberger S, Wenninger-Weinzierl A, Poplimont H, Sturtzel C, Schmitner N, et al.
Dis Model Mech . 2025 Feb; 18(2). PMID: 40014051
Owing to their high efficacy, antimitotic chemotherapeutics are the mainstay for most cancer treatments. However, these drugs do not discriminate between tumor and healthy cells, thus show dose-limiting toxicity and...
2.
Schelch K, Eder S, Zitta B, Phimmachanh M, Johnson T, Emminger D, et al.
Mol Oncol . 2022 Dec; 18(4):815-831. PMID: 36550787
Pleural mesothelioma (PM) is characterized by rapid growth, local invasion, and limited therapeutic options. The multifunctional oncoprotein Y-box-binding protein-1 (YB-1) is frequently overexpressed in cancer and its inhibition reduces aggressive...
3.
Georgantzoglou A, Poplimont H, Walker H, Lammermann T, Sarris M
J Cell Biol . 2022 Jun; 221(8). PMID: 35731205
Migrating cells must interpret chemical gradients to guide themselves within tissues. A long-held principle is that gradients guide cells via reorientation of leading-edge protrusions. However, recent evidence indicates that protrusions...
4.
Georgantzoglou A, Coombs C, Poplimont H, Walker H, Sarris M
J Vis Exp . 2020 Dec; (166). PMID: 33346191
Leukocyte guidance by chemical gradients is essential for immune responses. Neutrophils are the first cells to be recruited to sites of tissue damage where they execute crucial antimicrobial functions. Their...
5.
Poplimont H, Georgantzoglou A, Boulch M, Walker H, Coombs C, Papaleonidopoulou F, et al.
Curr Biol . 2020 Jun; 30(14):2761-2776.e7. PMID: 32502410
Neutrophils are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions. Within the damaged tissue, neutrophil migration behavior often switches from exploratory patrolling to coordinated swarming, giving rise...
6.
Coombs C, Georgantzoglou A, Walker H, Patt J, Merten N, Poplimont H, et al.
Nat Commun . 2020 Jan; 11(1):506. PMID: 31964873
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Coombs C, Georgantzoglou A, Walker H, Patt J, Merten N, Poplimont H, et al.
Nat Commun . 2019 Nov; 10(1):5166. PMID: 31727891
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient and self-resolving. Cell dispersal promotes resolution, but it remains unclear how transition...
8.
Iseda S, Takahashi N, Poplimont H, Nomura T, Seki S, Nakane T, et al.
J Virol . 2016 Apr; 90(14):6276-6290. PMID: 27122584
Unlabelled: Identifying human immunodeficiency virus type 1 (HIV-1) control mechanisms by neutralizing antibodies (NAbs) is critical for anti-HIV-1 strategies. Recent in vivo studies on animals infected with simian immunodeficiency virus...