Hugo Gonzalo
Overview
Explore the profile of Hugo Gonzalo including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
244
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0
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Recent Articles
1.
Gil-Sanchez A, Gonzalo H, Canudes M, Nogueras L, Gonzalez-Mingot C, Valcheva P, et al.
Pharmaceuticals (Basel)
. 2024 Apr;
17(4).
PMID: 38675419
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination and neuroinflammation, often accompanied by cognitive impairment. This study aims (1) to investigate the potential of glatiramer acetate (GA) as...
2.
Gonzalo H, Nogueras L, Gil-Sanchez A, Hervas J, Valcheva P, Gonzalez-Mingot C, et al.
Front Neurosci
. 2019 Sep;
13:938.
PMID: 31551694
Literature suggests that oxidative stress (OS) may be involved in the pathogenesis of multiple sclerosis (MS), in which the immune system is known to play a key role. However, to...
3.
Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis
Cacabelos D, Ayala V, Granado-Serrano A, Jove M, Torres P, Boada J, et al.
Neurobiol Dis
. 2016 Jan;
88:148-60.
PMID: 26805387
Background: Docosahexaenoic acid (DHA), a key lipid in nervous system homeostasis, is depleted in the spinal cord of sporadic amyotrophic lateral sclerosis (sALS) patients. However, the basis for such loss...
4.
Naudi A, Cabre R, Jove M, Ayala V, Gonzalo H, Portero-Otin M, et al.
Int Rev Neurobiol
. 2015 Sep;
122:133-89.
PMID: 26358893
Lipids stimulated and favored the evolution of the brain. Adult human brain contains a large amount of lipids, and the largest diversity of lipid classes and lipid molecular species. Lipidomics...
5.
Serrano J, Jove M, Gonzalo H, Pamplona R, Portero-Otin M
Int J Food Sci Nutr
. 2015 Aug;
66 Suppl 1:S22-30.
PMID: 26241008
Mechanism of action of bioactive compounds may be multiple, especially in the food matrix. Therefore, the interplay between these compounds and hosts' physiology, and the consequences of its continuous intake...
6.
Espinet C, Gonzalo H, Fleitas C, Menal M, Egea J
Curr Drug Targets
. 2015 Jan;
16(1):20-30.
PMID: 25563591
Neurotrophins are important neurotrophic factors involved in the survival, differentiation and function of a wide variety of neuron populations. A common feature for most neurotrophins is that they are synthesized...
7.
Gonzalo H, Brieva L, Tatzber F, Jove M, Cacabelos D, Cassanye A, et al.
J Neurochem
. 2012 Aug;
123(4):622-34.
PMID: 22924648
Metabolomic and lipidomic analyses have been used for the profiling of neurodegenerative processes, both in targeted and untargeted approaches. In this work we have applied these techniques to the study...
8.
Naudi A, Jove M, Ayala V, Cassanye A, Serrano J, Gonzalo H, et al.
Exp Diabetes Res
. 2012 Jan;
2012:696215.
PMID: 22253615
Oxidative stress has been implicated in diabetes long-term complications. In this paper, we summarize the growing evidence suggesting that hyperglycemia-induced overproduction of superoxide by mitochondrial electron transport chain triggers a...
9.
Serrano J, Cipak A, Boada J, Gonzalo H, Cacabelos D, Cassanye A, et al.
Acta Biochim Pol
. 2010 Jun;
57(2):193-8.
PMID: 20532253
A previous report from our group had shown in vitro a direct interaction between peroxidases and dietary antioxidants at physiological concentrations, where in the absence of H(2)O(2), the antioxidants could...
10.
Portero-Otin M, Pamplona R, Boada J, Jove M, Gonzalo H, Buleon M, et al.
Biochem Biophys Res Commun
. 2008 Feb;
368(3):528-35.
PMID: 18243127
Renin angiotensin system (RAS) worsens diabetic nephropathy (DN) by increasing oxidative stress. We compared the effect of three different RAS inhibitors: the angiotensin converting enzyme inhibitor Ramipril, the vasopeptidase inhibitor...