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Hugo D Lujan

Explore the profile of Hugo D Lujan including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 602
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Recent Articles
1.
Engeroff P, Belbezier A, Vaineau R, Fourcade G, Lujan H, Bellier B, et al.
Allergy . 2024 Dec; PMID: 39692165
No abstract available.
2.
Midlej V, Tenaglia A, Lujan H, De Souza W
Cells . 2024 Sep; 13(18. PMID: 39329722
(, ) is a protozoan parasite that inhabits the lumen of the upper small intestine of vertebrates, causing chronic abdominal pains and severe diarrhea, symptoms of giardiasis, a persistent and...
3.
Nibeyro G, Baronetto V, Folco J, Pastore P, Girotti M, Prato L, et al.
Front Immunol . 2023 Aug; 14:1094236. PMID: 37564650
Introduction: Identification of tumor specific neoantigen (TSN) immunogenicity is crucial to develop peptide/mRNA based anti-tumoral vaccines and/or adoptive T-cell immunotherapies; thus, accurate in-silico classification/prioritization proves critical for cost-effective clinical applications....
4.
Tenaglia A, Lujan L, Rios D, Molina C, Midlej V, Iribarren P, et al.
Nat Commun . 2023 May; 14(1):2537. PMID: 37137944
The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow...
5.
Rodriguez-Walker M, Molina C, Lujan L, Saura A, Jerlstrom-Hultqvist J, Svard S, et al.
Genomics . 2022 Aug; 114(5):110462. PMID: 35998788
Giardia lamblia encodes several families of cysteine-rich proteins, including the Variant-specific Surface Proteins (VSPs) involved in the process of antigenic variation. Their characteristics, definition and relationships are still controversial. An...
6.
Krakovka S, Ranjbarian F, Lujan L, Saura A, Larsen N, Jimenez-Gonzalez A, et al.
J Biol Chem . 2022 May; 298(6):102028. PMID: 35568200
Giardiasis is a diarrheal disease caused by the unicellular parasite Giardia intestinalis, for which metronidazole is the main treatment option. The parasite is dependent on exogenous deoxyribonucleosides for DNA replication...
7.
Bellier B, Saura A, Lujan L, Molina C, Lujan H, Klatzmann D
Front Immunol . 2022 Mar; 13:837443. PMID: 35281065
An ideal protective vaccine against SARS-CoV-2 should not only be effective in preventing disease, but also in preventing virus transmission. It should also be well accepted by the population and...
8.
Fernandez E, Mahmoud Y, Veigas F, Rocha D, Miranda M, Merlo J, et al.
Brief Bioinform . 2020 Dec; 22(4). PMID: 33320931
The accurate quantification of tumor-infiltrating immune cells turns crucial to uncover their role in tumor immune escape, to determine patient prognosis and to predict response to immune checkpoint blockade. Current...
9.
Del Carmen Serradell M, Rupil L, Lujan H
Medicina (B Aires) . 2019 Dec; 79(Spec 6/1):559-563. PMID: 31864226
The international spread of infectious diseases is a global problem of health security. Vaccination is one of the most successful and profitable health interventions. Oral immunization has significant advantages over...
10.
Serradell M, Rupil L, Martino R, Prucca C, Carranza P, Saura A, et al.
Nat Commun . 2019 Jan; 10(1):361. PMID: 30664644
Intestinal and free-living protozoa, such as Giardia lamblia, express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects the parasite inside the host's intestine. Here we show...