Hubert Li
Overview
Explore the profile of Hubert Li including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
399
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Carney D, Leffler A, Bell J, Chandrasinghe A, Cheng C, Chang E, et al.
Bioorg Med Chem
. 2024 Mar;
103:117577.
PMID: 38518735
Small-molecule antivirals that prevent the replication of the SARS-CoV-2 virus by blocking the enzymatic activity of its main protease (Mpro) are and will be a tenet of pandemic preparedness. However,...
2.
Zhang Y, Vass M, Shi D, Abualrous E, Chambers J, Chopra N, et al.
J Chem Inf Model
. 2023 Mar;
63(6):1656-1667.
PMID: 36897766
The recently developed AlphaFold2 (AF2) algorithm predicts proteins' 3D structures from amino acid sequences. The open AlphaFold protein structure database covers the complete human proteome. Using an industry-leading molecular docking...
3.
Katz D, DiMattia M, Sindhikara D, Li H, Abraham N, Leffler A
Mar Drugs
. 2021 Jul;
19(7).
PMID: 34202022
Nicotinic acetylcholine receptor (nAChR) subtypes are key drug targets, but it is challenging to pharmacologically differentiate between them because of their highly similar sequence identities. Furthermore, α-conotoxins (α-CTXs) are naturally...
4.
Tan Y, Srivastava S, Won B, Kanteti R, Arif Q, Husain A, et al.
Oncogenesis
. 2019 Sep;
8(9):49.
PMID: 31484920
Squamous cell carcinoma (SCC) and malignant pleural mesothelioma (MPM) are thoracic malignancies with very poor prognosis and limited treatment options. It is an established fact that most of the solid...
5.
Li H, Sandhu M, Malkas L, Hickey R, Vaidehi N
J Chem Inf Model
. 2017 Nov;
57(12):3011-3021.
PMID: 29095607
Proliferating cell nuclear antigen (PCNA) is a member of the family of sliding clamp proteins that serves as a clamp during DNA repair, DNA replication, cell cycle control, and multiple...
6.
Choy C, Ansari K, Neman J, Hsu S, Duenas M, Li H, et al.
Breast Cancer Res
. 2017 Apr;
19(1):51.
PMID: 28446206
Background: Patients with primary breast cancer that is positive for human epidermal growth factor receptor 2 (Her2+) have a high risk of developing metastases in the brain. Despite gains with...
7.
Nedjai B, Viney J, Li H, Hull C, Anderson C, Horie T, et al.
Br J Pharmacol
. 2014 Nov;
172(7):1822-33.
PMID: 25425280
Background And Purpose: The chemokine receptor CXCR3 is implicated in a variety of clinically important diseases, notably rheumatoid arthritis and atherosclerosis. Consequently, antagonists of CXCR3 are of therapeutic interest. In...
8.
Li H, Kasam V, Tautermann C, Seeliger D, Vaidehi N
J Chem Inf Model
. 2014 Apr;
54(5):1391-400.
PMID: 24762202
Protein-protein interactions are implicated in the pathogenesis of many diseases and are therefore attractive but challenging targets for drug design. One of the challenges in development is the identification of...
9.
Neman J, Termini J, Wilczynski S, Vaidehi N, Choy C, Kowolik C, et al.
Proc Natl Acad Sci U S A
. 2014 Jan;
111(3):984-9.
PMID: 24395782
Dispersion of tumors throughout the body is a neoplastic process responsible for the vast majority of deaths from cancer. Despite disseminating to distant organs as malignant scouts, most tumor cells...
10.
Bhattacharya S, Lam A, Li H, Balaraman G, Niesen M, Vaidehi N
Proteins
. 2012 Oct;
81(5):729-39.
PMID: 23042299
We present a critical assessment of the performance of our homology model refinement method for G protein-coupled receptors (GPCRs), called LITICon that led to top ranking structures in a recent...