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Hua-Rong Lu

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Articles 5
Citations 70
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Recent Articles
1.
Lu H, Seo M, Kreir M, Tanaka T, Yamoto R, Altrocchi C, et al.
Cells . 2023 Mar; 12(6). PMID: 36980298
Drug-induced seizure liability is a significant safety issue and the basis for attrition in drug development. Occurrence in late development results in increased costs, human risk, and delayed market availability...
2.
Xu G, Gaul M, Liu Z, DesJarlais R, Qi J, Wang W, et al.
Bioorg Med Chem Lett . 2020 Oct; 30(23):127602. PMID: 33038544
G-protein coupled receptor kinase 2 (GRK2), which is upregulated in the failing heart, appears to play a critical role in heart failure (HF) progression in part because enhanced GRK2 activity...
3.
Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, et al.
Toxicol Sci . 2018 May; 164(2):550-562. PMID: 29718449
Recent in vitro cardiac safety studies demonstrate the ability of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to detect electrophysiologic effects of drugs. However, variability contributed by unique approaches, procedures,...
4.
Lu H, Song S, Han K, Liu H, Chen S, Wang J, et al.
Zhongguo Zhong Xi Yi Jie He Za Zhi . 2015 Nov; 35(9):1109-12. PMID: 26591368
Objective: To observe whether adenosine Al receptor (Al R) mediated neuroprotection of Shenmai Injection (SI) on rat cerebral ischemia/reperfusion (I/R) injury. Methods: The focal cerebral I/R model was established by...
5.
Li L, Jiang K, Tan P, Wang A, Kong Q, Wang C, et al.
Asian Pac J Cancer Prev . 2015 May; 16(9):4077-80. PMID: 25987090
The chemokine receptor 4 (CXCR4) has been widely used in diagnosis and prognosis of colorectal cancer (CRC). However, there is no current consensus on the impact of CXCR4 on CRC...