Hongtu Hu
Overview
Explore the profile of Hongtu Hu including associated specialties, affiliations and a list of published articles.
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14
Citations
34
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Recent Articles
1.
Hu H, Ding G, Liang W
Food Funct
. 2025 Mar;
PMID: 40047381
Diabetic Kidney Disease (DKD) is a common and serious complication of diabetes, particularly Type 2 Diabetes Mellitus (T2DM), which significantly contributes to patient morbidity and mortality. The limitations of traditional...
2.
Zhu Z, Cao Y, Jian Y, Hu H, Yang Q, Hao Y, et al.
Nat Commun
. 2025 Feb;
16(1):1528.
PMID: 39934147
Ectopic lipid deposition, mitochondrial injury, and inflammatory responses contribute to the development of diabetic kidney disease (DKD); however, the mechanistic link between these processes remains unclear. In this study, we...
3.
Li W, Zhang Z, Peng Z, Hu H, Cui X, Zhu Z, et al.
J Am Soc Nephrol
. 2025 Feb;
PMID: 39932793
Background: Diabetic kidney disease (DKD) is characterized by progressive injury to glomerular podocytes due to sustained mechanical stress within the glomerulus. Piezo proteins, acting as cellular mechanosensors, play a pivotal...
4.
Hu H, Hu J, Chen Z, Yang K, Zhu Z, Hao Y, et al.
Adv Sci (Weinh)
. 2024 Oct;
11(46):e2405153.
PMID: 39441040
Diabetic Kidney Disease (DKD), a major precursor to end-stage renal disease, involves mitochondrial dysfunction in proximal renal tubular cells (PTCs), contributing to its pathogenesis. Estrogen-related receptor α (ERRα) is essential...
5.
Hu H, Li W, Hao Y, Peng Z, Zou Z, Wei J, et al.
Cell Rep Med
. 2024 Aug;
5(8):101690.
PMID: 39168099
Hyperuricemic nephropathy (HN) is a global metabolic disorder characterized by uric acid (UA) metabolism dysfunction, resulting in hyperuricemia (HUA) and tubulointerstitial fibrosis (TIF). Sodium-dependent glucose transporter 2 inhibitor, dapagliflozin, has...
6.
Zhou H, Liang W, Hu H, Liu Z, Chu F, Ding G
Clin Exp Immunol
. 2024 Aug;
218(2):120-135.
PMID: 39139142
Ongoing therapeutic advances in antineutrophil cytoplasmic antibody-associated vasculitis (AAV) have significantly reduced the risk of death in AAV, but 30%-50% of patients still relapse. Relapse is a major problem in...
7.
Yang K, Liang W, Hu H, Zhang Z, Hao Y, Song Z, et al.
Cell Signal
. 2024 Jul;
122:111308.
PMID: 39059756
Background: The protection of the diabetic kidney by Empagliflozin (EMPA) is attributed to its interaction with the sodium glucose cotransporter 2 located on proximal tubular epithelial cells (PTECs). Estrogen-related receptor...
8.
Hu J, Zhu Z, Zhang Z, Hu H, Yang Q
Life Sci
. 2024 May;
349:122722.
PMID: 38754814
Aims: Steroidogenic acute regulatory (StAR)-related lipid transfer domain-3 (STARD3) is a sterol-binding protein that facilitates cholesterol transport between cellular organelles. Cholesterol accumulation in podocytes directly contributes to the pathogenesis of...
9.
Hu H, Zhang Z, Liu Z, Chu F, Ran J, Liang W
Kidney Dis (Basel)
. 2024 Feb;
10(1):51-60.
PMID: 38322631
Introduction: Perirenal fat is a pad that fills the retroperitoneal space outside the kidney, which affects kidney function in various ways. However, the association between perirenal fat and IgA nephropathy...
10.
Hao Y, Fan Y, Feng J, Zhu Z, Luo Z, Hu H, et al.
Cell Commun Signal
. 2024 Jan;
22(1):26.
PMID: 38200543
Background: Cardiolipin (CL) plays a critical role in maintaining mitochondrial membrane integrity and overall mitochondrial homeostasis. Recent studies have suggested that mitochondrial damage resulting from abnormal cardiolipin remodelling is associated...