Jijia Hu
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Explore the profile of Jijia Hu including associated specialties, affiliations and a list of published articles.
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30
Citations
325
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Recent Articles
1.
Zhu Z, Cao Y, Jian Y, Hu H, Yang Q, Hao Y, et al.
Nat Commun
. 2025 Feb;
16(1):1528.
PMID: 39934147
Ectopic lipid deposition, mitochondrial injury, and inflammatory responses contribute to the development of diabetic kidney disease (DKD); however, the mechanistic link between these processes remains unclear. In this study, we...
2.
Hu H, Hu J, Chen Z, Yang K, Zhu Z, Hao Y, et al.
Adv Sci (Weinh)
. 2024 Oct;
11(46):e2405153.
PMID: 39441040
Diabetic Kidney Disease (DKD), a major precursor to end-stage renal disease, involves mitochondrial dysfunction in proximal renal tubular cells (PTCs), contributing to its pathogenesis. Estrogen-related receptor α (ERRα) is essential...
3.
Zhang L, Tian M, Zhang M, Li C, Wang X, Long Y, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(36):e2405325.
PMID: 39083268
Renal tubular epithelial cells (TECs) undergo an energy-related metabolic shift from fatty acid oxidation to glycolysis during chronic kidney disease (CKD) progression. However, the mechanisms underlying this burst of glycolysis...
4.
Yang K, Liang W, Hu H, Zhang Z, Hao Y, Song Z, et al.
Cell Signal
. 2024 Jul;
122:111308.
PMID: 39059756
Background: The protection of the diabetic kidney by Empagliflozin (EMPA) is attributed to its interaction with the sodium glucose cotransporter 2 located on proximal tubular epithelial cells (PTECs). Estrogen-related receptor...
5.
Hu J, Zhu Z, Zhang Z, Hu H, Yang Q
Life Sci
. 2024 May;
349:122722.
PMID: 38754814
Aims: Steroidogenic acute regulatory (StAR)-related lipid transfer domain-3 (STARD3) is a sterol-binding protein that facilitates cholesterol transport between cellular organelles. Cholesterol accumulation in podocytes directly contributes to the pathogenesis of...
6.
Cao Y, Chen X, Zhu Z, Luo Z, Hao Y, Yang X, et al.
Cell Death Dis
. 2024 Mar;
15(3):217.
PMID: 38485717
Recently, innate immunity and inflammation were recognized as the key factors for acute kidney injury (AKI) caused by sepsis, which is closely related to high mortality. Stimulator of interferon genes...
7.
Luo Z, Chen Z, Hu J, Ding G
Metabolism
. 2023 Nov;
150:155718.
PMID: 37925142
Podocytes are critical for maintaining permselectivity of the glomerular filtration barrier, and podocyte injury is a major cause of proteinuria in various primary and secondary glomerulopathies. Lipid dysmetabolism and inflammatory...
8.
Huang X, Chen Z, Luo Z, Hao Y, Feng J, Zhu Z, et al.
Ren Fail
. 2023 Jul;
45(1):2230318.
PMID: 37427767
Podocytes play a critical role in maintaining normal glomerular filtration, and podocyte loss from the glomerular basement membrane (GBM) initiates and worsens chronic kidney disease (CKD). However, the exact mechanism...
9.
Yang X, Chen Z, Luo Z, Yang D, Hao Y, Hu J, et al.
Cell Signal
. 2023 Jun;
109:110777.
PMID: 37329999
An increasing number of studies have shown that immune inflammatory response plays a vital role in diabetic kidney disease (DKD). Nod-like receptor protein 3 (NLRP3) inflammasome-dependent inflammatory response is a...
10.
Hu J, Zhang Z, Hu H, Yang K, Zhu Z, Yang Q, et al.
Cell Prolif
. 2023 Apr;
56(11):e13479.
PMID: 37057309
Alteration of metabolic phenotype in podocytes directly contributes to the development of albuminuria and renal injury in conditions of diabetic kidney disease (DKD). This study aimed to identify and evaluate...