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Hongping Ye

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Articles 31
Citations 282
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Recent Articles
1.
Zhang L, Salekeen R, Soto-Palma C, Elsallabi O, Ye H, Hughes B, et al.
bioRxiv . 2024 Oct; PMID: 39463954
Cellular senescence is a key driver of the aging process and contributes to tissue dysfunction and age-related pathologies. Senolytics have emerged as a promising therapeutic intervention to extend healthspan and...
2.
Takahashi H, Perez-Canamas A, Lee C, Ye H, Han X, Strittmatter S
Commun Biol . 2024 Sep; 7(1):1088. PMID: 39237682
TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer's disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies...
3.
Takahashi H, Bhagwagar S, Nies S, Ye H, Han X, Chiasseu M, et al.
Nat Commun . 2024 Feb; 15(1):1434. PMID: 38365772
Comorbid proteinopathies are observed in many neurodegenerative disorders including Alzheimer's disease (AD), increase with age, and influence clinical outcomes, yet the mechanisms remain ill-defined. Here, we show that reduction of...
4.
Scarr D, Lovblom E, Ye H, Liu H, Bakhsh A, Verhoeff N, et al.
Diabetes Res Clin Pract . 2023 Nov; 207:111031. PMID: 38036220
Aims: We aimed to determine if ketone production and excretion are increased even at mild fasting hyperglycemia in type 1 diabetes (T1D) and if these are modified by ketoacidosis risk...
5.
Qiu X, Ye H, Li X, Li D, Jiang L, Liu R, et al.
Mol Metab . 2023 Nov; 78:101836. PMID: 37949355
Objective: Tumor cells hijack inflammatory mechanisms to promote their own growth. IL-6 is one of the major cytokines, and is frequently upregulated in tumors. The pentose phosphate pathway (PPP) generates...
6.
Takahashi H, Perez-Canamas A, Ye H, Han X, Strittmatter S
bioRxiv . 2023 Sep; PMID: 37745346
TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer's disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies...
7.
Kwan B, Fuhrer T, Montemayor D, Fink J, He J, Hsu C, et al.
BMC Bioinformatics . 2023 Feb; 24(1):57. PMID: 36803209
Background: The growing amount of high dimensional biomolecular data has spawned new statistical and computational models for risk prediction and disease classification. Yet, many of these methods do not yield...
8.
Du Y, Wang J, Li S, Dennis B, Meireles C, Siddiqui N, et al.
Contemp Clin Trials . 2022 Jul; 119:106845. PMID: 35809772
Background: The obesity epidemic is a public health concern, as it is associated with a variety of chronic conditions. The ketogenic diet has drawn much scientific and public attention. However,...
9.
Zhang J, Fuhrer T, Ye H, Kwan B, Montemayor D, Tumova J, et al.
Am J Nephrol . 2022 Feb; 53(2-3):215-225. PMID: 35196658
Introduction: Metabolomics could offer novel prognostic biomarkers and elucidate mechanisms of diabetic kidney disease (DKD) progression. Via metabolomic analysis of urine samples from 995 CRIC participants with diabetes and state-of-the-art...
10.
Liu H, Sridhar V, Montemayor D, Lovblom L, Lytvyn Y, Ye H, et al.
Diabetes Obes Metab . 2021 Jul; 23(11):2466-2475. PMID: 34251085
Aim: To examine the impact of the sodium-glucose co-transporter-2 inhibitor, empagliflozin, on plasma and urine metabolites in participants with type 1 diabetes. Material And Methods: Participants (n = 40, 50%...