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Hongjing Sun

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Recent Articles
1.
Sun H, Kim M, Ong Y, Dimofte A, Singhal S, Busch T, et al.
Photochem Photobiol . 2025 Jan; PMID: 39838651
Photodynamic therapy (PDT) has shown promise as an adjuvant treatment for malignant pleural mesothelioma when combined with surgical resection. Accurate light dosimetry is critical for treatment efficacy. This study presents...
2.
Yang W, Johnson M, Lu B, Sourvanos D, Sun H, Dimofte A, et al.
Antioxidants (Basel) . 2025 Jan; 13(12). PMID: 39765787
The direct detection of singlet-state oxygen (O) constitutes the holy grail dosimetric method for type-II photodynamic therapy (PDT), a goal that can be quantified using multispectral singlet oxygen near-infrared luminescence...
3.
Sun H, Ong Y, Kim M, Dimofte A, Singhal S, Cengel K, et al.
Antioxidants (Basel) . 2025 Jan; 13(12). PMID: 39765767
Photodynamic therapy (PDT) relies on the interactions between light, photosensitizers, and tissue oxygen to produce cytotoxic reactive oxygen species (ROS), primarily singlet oxygen (O) through Type II photochemical reactions, along...
4.
Yang W, Rastogi V, Sun H, Sharma D, Wilson B, Hadfield R, et al.
Proc SPIE Int Soc Opt Eng . 2024 Feb; 12359. PMID: 38419618
Direct detection of singlet-state oxygen ([O]) constitutes the holy grail dosimetric method for type II PDT, a goal that can be quantified using multispectral singlet oxygen dosimetry (MSOLD). However, the...
5.
Sourvanos D, Sun H, Zhu T, Dimofte A, Byrd B, Busch T, et al.
Photodiagnosis Photodyn Ther . 2024 Feb; 46:104014. PMID: 38346466
Objective: The primary aim was to investigate emerging 3D printing and optical acquisition technologies to refine and enhance photodynamic therapy (PDT) dosimetry in the management of malignant pleural mesothelioma (MPM)....
6.
Sun H, Ong Y, Yang W, Sourvanos D, Dimofte A, Busch T, et al.
J Biomed Opt . 2024 Jan; 29(1):018001. PMID: 38223299
Significance: Photodynamic therapy (PDT) is an established cancer treatment utilizing light-activated photosensitizers (PS). Effective treatment hinges on the PDT dose-dependent on PS concentration and light fluence-delivered over time. We introduce...
7.
Sun H, Yang W, Ong Y, Busch T, Zhu T
Cancers (Basel) . 2023 Dec; 15(23). PMID: 38067385
This study investigates the effect of fractionated (two-part) PDT on the long-term local control rate (LCR) using the concentration of reactive oxygen species ([ROS]) as a dosimetry quantity. Groups with...
8.
Sun H, Rastogi V, Zhu T
Proc SPIE Int Soc Opt Eng . 2023 Jun; 12359. PMID: 37378071
Photodynamic therapy (PDT) is an established modality for cancer treatment, and reactive oxygen species explicit dosimetry (ROSED), based on direct measurements of in-vivo light fluence (rate), in-vivo photofrin concentration, and...
9.
Sun H, Sourvanos D, Potasek M, Parilov G, Beesonk C, Zhu T
Proc SPIE Int Soc Opt Eng . 2023 May; 12359. PMID: 37206987
Photodynamic therapy (PDT) has been used intraoperatively to treat patients with malignant pleural mesothelioma. For the efficiency of PDT, it is crucial to deliver light doses uniformly. The current procedure...
10.
Sourvanos D, Sun H, Cengel K, Fiorellini J, Zhu T
Proc SPIE Int Soc Opt Eng . 2023 May; 12359. PMID: 37206986
We have developed a novel scanning protocol for a life-sized human phantom model using handheld three-dimensional (3D) surface acquisition devices. This technology will be utilized to develop light fluence modeling...