Hon Yan Kelvin Yip
Overview
Explore the profile of Hon Yan Kelvin Yip including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
96
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0
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Recent Articles
1.
Yip H, Shin S, Chee A, Ang C, Rossello F, Wong L, et al.
NPJ Precis Oncol
. 2024 Jan;
8(1):20.
PMID: 38273040
Utility of PI3Kα inhibitors like BYL719 is limited by the acquisition of genetic and non-genetic mechanisms of resistance which cause disease recurrence. Several combination therapies based on PI3K inhibition have...
2.
Yip H, Papa A
STAR Protoc
. 2021 Sep;
2(3):100765.
PMID: 34485937
3D cultures of mammary epithelial cells purified from murine models provide a unique resource to study genetically defined breast cancer and response to targeted therapies. Here, we describe step-by-step experimental...
3.
Yip H, Papa A
Cells
. 2021 Apr;
10(3).
PMID: 33809714
Molecular alterations in cancer genes and associated signaling pathways are used to inform new treatments for precision medicine in cancer. Small molecule inhibitors and monoclonal antibodies directed at relevant cancer-related...
4.
Srijakotre N, Liu H, Nobis M, Man J, Yip H, Papa A, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(45):28056-28067.
PMID: 33097662
The Rac-GEF, P-Rex1, activates Rac1 signaling downstream of G protein-coupled receptors and PI3K. Increased P-Rex1 expression promotes melanoma progression; however, its role in breast cancer is complex, with differing reports...
5.
Yip H, Tan C, Hirokawa Y, Burgess A
PLoS One
. 2018 Jun;
13(6):e0199412.
PMID: 29928021
Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon mesenchymal cell feeder layers can stimulate colon crypts to form...