Hoa T N Phan
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Explore the profile of Hoa T N Phan including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
22
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Recent Articles
1.
Vo N, Tran C, Tran N, Nguyen N, Nguyen T, Ho D, et al.
J Extracell Vesicles
. 2024 May;
13(5):e12454.
PMID: 38760878
Extracellular vesicles (EVs) are emerging as a promising drug delivery vehicle as they are biocompatible and capable of targeted delivery. However, clinical translation of EVs remains challenging due to the...
2.
Simien J, Orellana G, Phan H, Hu Y, Kurth E, Ruf C, et al.
J Phys Chem B
. 2023 Mar;
127(11):2457-2465.
PMID: 36912891
Obesity is a classified epidemic, increasing the risk of secondary diseases such as diabetes, inflammation, cardiovascular disease, and cancer. The pleiotropic hormone leptin is the proposed link for the gut-brain...
3.
Phan H, Loomis J, Abraham S, He Q, Bastepe M, Smrcka A
J Biol Chem
. 2022 Jun;
298(8):102134.
PMID: 35709985
Extra-large stimulatory Gα (XLα) is a large variant of G protein α subunit (Gα) that uses an alternative promoter and thus differs from Gα at the first exon. XLα activation...
4.
Phan H, Kim N, Wei W, Tall G, Smrcka A
Sci Signal
. 2021 Dec;
14(713):eabj4243.
PMID: 34905385
Activating mutations in Gα proteins are frequent in uveal melanoma, the most common eye cancer arising from the uveal tract. A small proportion of uveal melanomas have a D630Y mutation...
5.
Phan H, Jackson W, Shaw V, Watts S, Neubig R
Mol Pharmacol
. 2019 Oct;
96(6):826-834.
PMID: 31645376
Regulator of G protein signaling 2 (RGS2) plays a role in reducing vascular contraction and promoting relaxation due to its GTPase accelerating protein activity toward Gq. Previously, we identified four...
6.
Phan H, Sjogren B, Neubig R
Mol Pharmacol
. 2017 Aug;
92(4):451-458.
PMID: 28784619
Regulator of G protein signaling 2 (RGS2) plays a significant role in alleviating vascular contraction and promoting vascular relaxation due to its GTPase accelerating protein activity toward Gq. Mice lacking...