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Hitesh Bhagavanbhai Mangukiya

Explore the profile of Hitesh Bhagavanbhai Mangukiya including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 49
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Recent Articles
1.
Rosen E, Mangukiya H, Elfineh L, Stockgard R, Krona C, Gerlee P, et al.
Commun Biol . 2023 Apr; 6(1):402. PMID: 37055469
Cancer cell migration is a driving mechanism of invasion in solid malignant tumors. Anti-migratory treatments provide an alternative approach for managing disease progression. However, we currently lack scalable screening methods...
2.
Saidi Mashausi D, Roy D, Mangukiya H, Merugu S, Raza G, Yunus F, et al.
Biochem Biophys Res Commun . 2022 May; 637:358-364. PMID: 35595575
Hemophilia A is a bleeding disorder caused by quantitative or qualitative deficiencies in coagulation factor VIII (FVIII). Low FVIII expression due to its unstable mRNA and binding with immunoglobulin-binding protein...
3.
Merugu S, Zhou B, Mangukiya H, Negi H, Ghulam R, Roy D, et al.
Biochem Biophys Res Commun . 2021 Aug; 573:86-92. PMID: 34399098
Anterior gradient 2 (AGR2) is often overexpressed in several types of cancer. AGR2 is cytoplasmic or secreted as an extracellular signal. Intracellular AGR2 properties and role in cancer have been...
4.
Raza G, Yunus F, Mangukiya H, Merugu S, Saidi Mashausi D, Zeling W, et al.
Int Immunopharmacol . 2020 Nov; 90:107155. PMID: 33243603
IL13Rα2 shows high expression in different types of tumors and can be a target for cancer therapy in humans due to its poor prognosis. The aim of our study is...
5.
Mangukiya H, Negi H, Merugu S, Sehar Q, Saidi Mashausi D, Yunus F, et al.
Cell Adh Migr . 2019 Nov; 13(1):332-344. PMID: 31710263
The most prominent cancer-associated fibroblasts (CAFs) in tumor stroma is known to form a protective structure to support tumor growth. Anterior gradient-2 (AGR2), a tumor secretory protein is believed to...
6.
Negi H, Merugu S, Mangukiya H, Li Z, Zhou B, Sehar Q, et al.
Cancer Lett . 2019 Jan; 449:125-134. PMID: 30685412
Increased drug resistance and acute side effects on normal organs are the major disadvantages of traditional cancer chemotherapy and radiotherapy. This has increased the focus on targeted therapeutic strategies such...
7.
Zhu Q, Mangukiya H, Saidi Mashausi D, Guo H, Negi H, Merugu S, et al.
FEBS J . 2017 Jul; 284(17):2856-2869. PMID: 28665039
Anterior gradient 2 (AGR2), a member of protein disulfide isomerase (PDI) family, is both located in cytoplasm and secreted into extracellular matrix. The orthologs of AGR2 have been linked to...