Hisashi Fujioka
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Explore the profile of Hisashi Fujioka including associated specialties, affiliations and a list of published articles.
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119
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4922
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Recent Articles
1.
Gao J, Ding M, Xiyang Y, Qin S, Shukla D, Xu J, et al.
J Immunol
. 2025 Mar;
214(2):238-252.
PMID: 40073244
Mitochondrial antiviral-signaling protein (MAVS) is a key adapter protein required for inducing type I interferons (IFN-Is) and other antiviral effector molecules. The formation of MAVS aggregates on mitochondria is essential...
2.
Dantas W, Heintz E, Zunica E, Mey J, Erickson M, Belmont K, et al.
J Cachexia Sarcopenia Muscle
. 2025 Mar;
16(2):e13763.
PMID: 40035128
Background: Activation of mitochondrial fission and quality control occur early in the onset of insulin resistance in human skeletal muscle. We hypothesized that differences in mitochondrial dynamics, structure and bioenergetics...
3.
Sridharan P, Koh Y, Miller E, Hu D, Chakraborty S, Tripathi S, et al.
Cell Rep Med
. 2024 Sep;
5(9):101715.
PMID: 39241772
Progression of acute traumatic brain injury (TBI) into chronic neurodegeneration is a major health problem with no protective treatments. Here, we report that acutely elevated mitochondrial fission after TBI in...
4.
Wang W, Ma X, Bhatta S, Shao C, Zhao F, Fujioka H, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(51):e2316823120.
PMID: 38091289
Mitochondrial dysfunction plays a critical role in the pathogenesis of Alzheimer's disease (AD). Mitochondrial proteostasis regulated by chaperones and proteases in each compartment of mitochondria is critical for mitochondrial function,...
5.
Sakanoue I, Okamoto T, Ayyat K, Yun J, Farver C, Fujioka H, et al.
Transplantation
. 2023 Sep;
108(3):669-678.
PMID: 37726888
Background: Ex vivo lung perfusion expands the lung transplant donor pool and extends preservation time beyond cold static preservation. We hypothesized that repeated regular ex vivo lung perfusion would better...
6.
Sam-Yellowe T, Asraf M, Peterson J, Fujioka H
Microorganisms
. 2023 Aug;
11(8).
PMID: 37630505
sp. (ATCC 50594) is a free-living biflagellate predator closely related to pathogenic Apicomplexa such as , and . sp. (ATCC 50594) obtain nutrients by preying on using myzocytosis. The organization...
7.
Lu Y, Fujioka H, Wang W, Zhu X
Biochim Biophys Acta Mol Basis Dis
. 2023 Aug;
1869(8):166841.
PMID: 37558011
Mitochondrial dysfunction plays an important role in the pathogenesis of Alzheimer's disease (AD), the most common neurodegenerative disease. Prior studies suggested impaired mitochondrial biogenesis likely contributes to mitochondrial dysfunction in...
8.
Wang W, Zhao F, Lu Y, Siedlak S, Fujioka H, Feng H, et al.
Acta Neuropathol Commun
. 2023 Apr;
11(1):54.
PMID: 37004141
Loss of synapses is the most robust pathological correlate of Alzheimer's disease (AD)-associated cognitive deficits, although the underlying mechanism remains incompletely understood. Synaptic terminals have abundant mitochondria which play an...
9.
Islam S, Do M, Frank B, Hom G, Wheeler S, Fujioka H, et al.
J Biol Chem
. 2022 Aug;
298(10):102417.
PMID: 36037967
Γ-Crystallins play a major role in age-related lens transparency. Their destabilization by mutations and physical chemical insults are associated with cataract formation. Therefore, drugs that increase their stability should have...
10.
Yan T, Liang J, Gao J, Wang L, Fujioka H, Zhu X, et al.
Nat Commun
. 2022 Jul;
13(1):4006.
PMID: 35817794
No abstract available.