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Hiroshi Katsuki

Explore the profile of Hiroshi Katsuki including associated specialties, affiliations and a list of published articles. Areas
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Articles 165
Citations 1765
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Recent Articles
11.
Nakanishi S, Kinoshita K, Kurauchi Y, Seki T, Kimura Y, Suzuki M, et al.
Eur J Pharmacol . 2023 Jul; 954:175899. PMID: 37392831
Peretinoin is an acyclic retinoid that stimulates retinoic acid receptors (NR1Bs) and produces therapeutic effects on hepatocellular cancer. We have previously shown that NR1B agonists such as Am80 and all...
12.
Idera A, Sharkey L, Kurauchi Y, Kadoyama K, Paulson H, Katsuki H, et al.
J Pharmacol Sci . 2023 May; 152(3):182-192. PMID: 37257946
Missense mutations of ubiquilin 2 (UBQLN2) have been identified to cause X-linked amyotrophic lateral sclerosis (ALS). Proteasome-mediated protein degradation is reported to be impaired by ALS-associated mutations of UBQLN2. However,...
13.
Suzuki K, Koyama H, Nakamura N, Kimura Y, Ogata A, Ikenuma H, et al.
Bioorg Med Chem Lett . 2023 Mar; 85:129212. PMID: 36871703
Recently, retinoid actions on the central nervous system (CNS) have attracted considerable attention from the perspectives of brain disease diagnosis and drug development. Firstly, we successfully synthesized [C]peretinoin esters (methyl,...
14.
Kurauchi Y, Ohta Y, Matsuda K, Sanematsu W, Devkota H, Seki T, et al.
Nutrients . 2023 Feb; 15(3). PMID: 36771286
Matcha tea powder is believed to have various physiological benefits; however, its detailed mechanism of action has been poorly understood. Here, we investigated whether the mental state of mice, due...
15.
Atef Y, Kinoshita K, Ichihara Y, Ushida K, Kurauchi Y, Seki T, et al.
Biol Pharm Bull . 2022 Nov; 45(11):1699-1705. PMID: 36328505
Hydrogen sulfide and polysulfides are increasingly recognized as bioactive signaling molecules to produce various actions and regulate (patho)physiological processes. Here we examined the effects of sodium sulfide (NaS) and sodium...
16.
Maeda H, Ichimizu S, Watanabe H, Hamasaki K, Chikamatsu M, Murata R, et al.
Int J Biol Macromol . 2022 Sep; 221:1439-1452. PMID: 36126807
Innovations in oral immunotherapy have greatly advanced the therapeutic control of allergies. However, these therapeutic effects suffer from the fact that the amount of antigen delivered to antigen-presenting cells is...
17.
Yamada Y, Miwa T, Nakashima M, Shirakawa A, Ishii A, Namba N, et al.
Biomed Pharmacother . 2022 Sep; 155:113698. PMID: 36116252
Niemann-Pick disease type C (NPC) is a fatal disorder with abnormal intracellular cholesterol trafficking resulting in neurodegeneration and hepatosplenomegaly. A cyclic heptasaccharide with different degrees of substitution of 2-hydroxypropyl groups,...
18.
Kinoshita K, Yoshimizu A, Ichihara Y, Ushida K, Kotani S, Kurauchi Y, et al.
Sci Rep . 2022 Jun; 12(1):11009. PMID: 35773404
We have previously reported that amodiaquine, a compound that binds to the ligand-binding domain of a nuclear receptor Nurr1, attenuates inflammatory responses and neurological deficits after intracerebral hemorrhage (ICH) in...
19.
Ueda E, Ohta T, Konno A, Hirai H, Kurauchi Y, Katsuki H, et al.
Cells . 2022 Apr; 11(7). PMID: 35406792
Chaperone-mediated autophagy (CMA) is a pathway in the autophagy-lysosome protein degradation system. CMA impairment has been implicated to play a role in spinocerebellar ataxia (SCA) pathogenesis. D-cysteine is metabolized by...
20.
Guinto M, Haruta M, Kurauchi Y, Saigo T, Kurasawa K, Ryu S, et al.
J Biomed Opt . 2022 Feb; 27(2). PMID: 35166087
Significance: Intrinsic optical signals (IOS) generated in the cortical tissue as a result of various interacting metabolic processes are used extensively to elucidate the underlying mechanisms that govern neurovascular coupling....