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Yoichiro Isohama

Explore the profile of Yoichiro Isohama including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 687
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Recent Articles
1.
Sekiya T, Murakami K, Isohama Y
Biol Pharm Bull . 2024 Jul; 47(7):1307-1313. PMID: 39019610
Airway ciliary cells are components of the mucociliary transport system and play an important role in sweeping out small particles, such as bacteria and viruses, towards the oropharynx by the...
2.
Sekiya T, Murakami K, Isohama Y
J Pharmacol Sci . 2024 Apr; 155(2):21-28. PMID: 38677782
Goblet cell hyperplasia and increased mucus production are features of airway diseases, including asthma, and excess airway mucus often worsens these conditions. Even steroids are not uniformly effective in mucus...
3.
Tani H, Yamaga M, Sekiya T, Isohama Y, Koshino H, Nogawa T, et al.
J Agric Food Chem . 2023 Sep; 71(37):13805-13813. PMID: 37683090
The cough-suppressing effect of honey was demonstrated for the first time using a guinea pig model whereby cough was induced by citric acid and capsaicin, and a new pyrrolyl pyridoindole,...
4.
Muroi S, Isohama Y
Int J Mol Sci . 2021 Dec; 22(24). PMID: 34948308
Aquaporin-5 (AQP5) is selectively expressed in the apical membrane of exocrine glands, such as salivary, sweat, and submucosal airway glands, and plays important roles in maintaining their secretory functions. Because...
5.
Muroi S, Isohama Y
Int J Mol Sci . 2021 Dec; 22(24). PMID: 34948259
Aquaporin-5 (AQP5) is selectively expressed in the apical membrane of exocrine glands, such as salivary, lacrimal, and submucosal glands. It is important for the secretory function of exocrine glands because...
6.
Ishibashi J, Isohama Y
Biol Pharm Bull . 2021 Apr; 44(4):590-592. PMID: 33790109
MUC5AC overproduction is commonly observed in chronic inflammatory lung diseases and worsens these conditions. Therefore, drugs that inhibit MUC5AC production are urgently needed. To identify novel drugs directly inhibiting MUC5AC...
7.
Ishibashi J, Saito K, Ishizaki T, Horie I, Isohama Y
Biol Pharm Bull . 2021 Mar; 44(3):404-409. PMID: 33642548
Mucus hypersecretion is a hallmark of respiratory diseases, and excess airway mucus can worsen these conditions. Therefore, it is important to control the production of airway mucus in the treatment...
8.
Sasada M, Iyoda T, Asayama T, Suenaga Y, Sakai S, Kase N, et al.
Oncotarget . 2019 Aug; 10(48):4960-4972. PMID: 31452837
The family oncogenes (, , and ) contribute to the genesis of many human cancers. Among them, amplification of the gene and over-expression of N-Myc protein are the most reliable...
9.
Ohyama M, Horie I, Isohama Y, Azuma K, Adachi S, Minejima C, et al.
Inhal Toxicol . 2018 Jun; 30(4-5):149-158. PMID: 29860904
We examined the baseline pulmonary resistance (RLung), baseline dynamic lung compliance (Cdyn), cytokine inductions, and histological alterations in rats exposed to nitrous acid (HONO) with secondary products of nitrogen dioxide...
10.
Fujitsuka N, Tamai M, Tsuchiya K, Iizuka S, Tsuchiya N, Makino B, et al.
BMC Complement Altern Med . 2015 Dec; 15:451. PMID: 26703073
Background: Hydrarthrosis, which is associated with knee pain and limited range of motion, decreases the quality of life (QOL) of patients with osteoarthritis (OA). The Kampo medicine boiogito is prescribed...