Hirofumi Morihara
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Explore the profile of Hirofumi Morihara including associated specialties, affiliations and a list of published articles.
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14
Citations
81
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Recent Articles
1.
Mori S, Kimura R, Morihara H, Tomimatsu M, Fuchigami S, Matsumoto K, et al.
Am J Physiol Cell Physiol
. 2024 Nov;
328(1):C95-C106.
PMID: 39611549
As cardiomyocyte loss causes heart failure, inhibition of cardiomyocyte death may be a therapeutic strategy against heart failure. In this study, we have identified defender against cell death 1 (Dad1)...
2.
Morihara H, Yokoe S, Wakabayashi S, Takai S
FASEB Bioadv
. 2024 Nov;
6(11):565-579.
PMID: 39512841
Transmembrane protein 182 (TMEM182) is notably abundant in muscle and adipose tissue, but its role in the heart remains unknown. This study examined the contribution of TMEM182 in the differentiation...
3.
Kobayashi M, Tomoda K, Morihara H, Asahi M, Tetsuji Shimizu , Kumagai S
Heliyon
. 2023 Aug;
9(7):e17585.
PMID: 37539278
[This corrects the article DOI: 10.1016/j.heliyon.2022.e12009.].
4.
Matsuno M, Yokoe S, Nagatsuka T, Morihara H, Moriwaki K, Asahi M
Front Endocrinol (Lausanne)
. 2023 Apr;
14:1122125.
PMID: 37033243
-GlcNAc transferase (OGT) modulates many functions of proteins -GlcNAcylation that adds -linked β--acetylglucosamine (-GlcNAc) to the serine/threonine residues of proteins. However, the role of -GlcNAcylation in cardiac remodeling and function...
5.
Kobayashi M, Tomoda K, Morihara H, Asahi M, Tetsuji Shimizu , Kumagai S
Heliyon
. 2022 Dec;
8(12):e12009.
PMID: 36506411
Non-thermal atmospheric-pressure plasma has been used for biological applications, including sterilization and stimulation of cell growth and differentiation. Here, we demonstrate that plasma exposure influences the differentiation pattern of human...
6.
Daimon A, Morihara H, Tomoda K, Morita N, Koishi Y, Kanki K, et al.
Cell Transplant
. 2020 Dec;
29:963689720970456.
PMID: 33349053
Miscarriage is the most common complication of pregnancy, and about 1% of pregnant women suffer a recurrence. Using a widely used mouse miscarriage model, we previously showed that intravenous injection...
7.
Tsuruoka K, Wakabayashi S, Morihara H, Matsunaga N, Fujisaka Y, Goto I, et al.
Int J Cardiol
. 2020 May;
313:67-75.
PMID: 32402518
Background: Although immune checkpoint inhibitors (ICIs) have made an immense breakthrough in cancer therapeutics, they can exert unique, immune-related adverse events. Among them, myocarditis is less frequent, but it is...
8.
Wakabayashi S, Morihara H, Yokoe S, Nakagawa T, Moriwaki K, Tomoda K, et al.
J Biol Chem
. 2019 Nov;
294(51):19577-19588.
PMID: 31723030
Understanding the specific properties of human induced pluripotent stem cells (iPSCs) is important for quality control of iPSCs. Having incidentally discovered that overexpression of plasma membrane Na/H exchanger 1 (NHE1)...
9.
Morihara H, Obana M, Tanaka S, Kawakatsu I, Tsuchiyama D, Mori S, et al.
PLoS One
. 2017 Dec;
12(12):e0189948.
PMID: 29267336
Excessive levels of reactive oxygen species (ROS) and impaired Ca2+ homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several...
10.
Morihara H, Yamamoto T, Oiwa H, Tonegawa K, Tsuchiyama D, Kawakatsu I, et al.
J Cardiovasc Pharmacol Ther
. 2016 Nov;
22(3):273-282.
PMID: 27811197
Background: Phospholamban (PLN) inhibition enhances calcium cycling and is a potential novel therapy for heart failure (HF). Antisense oligonucleotides (ASOs) are a promising tool for unmet medical needs. Nonviral vector...