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Hilary P Browne

Explore the profile of Hilary P Browne including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 1926
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Recent Articles
1.
Shao Y, Garcia-Maurino C, Clare S, Dawson N, Mu A, Adoum A, et al.
Nat Microbiol . 2024 Sep; 9(10):2570-2582. PMID: 39242817
Human microbiota assembly commences at birth, seeded by both maternal and environmental microorganisms. Ecological theory postulates that primary colonizers dictate microbial community assembly outcomes, yet such microbial priority effects in...
2.
Browne H, Iqbal N, Osman M, Tigoi C, Lawley T, Gordon J, et al.
Nature . 2024 Jan; 625(7994):237-240. PMID: 38191714
No abstract available.
3.
Browne H, Shao Y, Lawley T
Curr Opin Microbiol . 2022 Jul; 69:102173. PMID: 35785616
Humans are colonised by a highly adapted microbiota with coevolved functions that promote human health, development and disease resistance. Acquisition and assembly of the microbiota start at birth and recent...
4.
Forster S, Liu J, Kumar N, Gulliver E, Gould J, Escobar-Zepeda A, et al.
Nat Commun . 2022 Mar; 13(1):1445. PMID: 35301310
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene transfer (HGT) events between human gut...
5.
Beresford-Jones B, Forster S, Stares M, Notley G, Viciani E, Browne H, et al.
Cell Host Microbe . 2021 Dec; 30(1):124-138.e8. PMID: 34971560
Human health and disease have increasingly been shown to be impacted by the gut microbiota, and mouse models are essential for investigating these effects. However, the compositions of human and...
6.
Mullineaux-Sanders C, Carson D, Hopkins E, Glegola-Madejska I, Escobar-Zepeda A, Browne H, et al.
mBio . 2021 Oct; 12(5):e0241021. PMID: 34609899
The gut microbiota plays a crucial role in susceptibility to enteric pathogens, including Citrobacter rodentium, a model extracellular mouse pathogen that colonizes the colonic mucosa. C. rodentium infection outcomes vary...
7.
Browne H, Almeida A, Kumar N, Vervier K, Adoum A, Viciani E, et al.
Genome Biol . 2021 Aug; 22(1):204. PMID: 34348764
Background: Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota. However, despite its importance, the genomic and biological adaptations underpinning...
8.
Kumar N, Browne H, Viciani E, Forster S, Clare S, Harcourt K, et al.
Nat Genet . 2019 Aug; 51(9):1315-1320. PMID: 31406348
Bacterial speciation is a fundamental evolutionary process characterized by diverging genotypic and phenotypic properties. However, the selective forces that affect genetic adaptations and how they relate to the biological changes...
9.
Forster S, Kumar N, Anonye B, Almeida A, Viciani E, Stares M, et al.
Nat Biotechnol . 2019 Feb; 37(2):186-192. PMID: 30718869
Understanding gut microbiome functions requires cultivated bacteria for experimental validation and reference bacterial genome sequences to interpret metagenome datasets and guide functional analyses. We present the Human Gastrointestinal Bacteria Culture...
10.
Browne H, Neville B, Forster S, Lawley T
Nat Rev Microbiol . 2017 Jun; 15(9):531-543. PMID: 28603278
Transmission of commensal intestinal bacteria between humans could promote health by establishing, maintaining and replenishing microbial diversity in the microbiota of an individual. Unlike pathogens, the routes of transmission for...