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Hideo Ohira

Explore the profile of Hideo Ohira including associated specialties, affiliations and a list of published articles. Areas
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Citations 335
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Recent Articles
1.
Ohira H, Oikawa D, Kurokawa Y, Aoki Y, Omura A, Kiyomoto K, et al.
Food Funct . 2022 Aug; 13(18):9285-9298. PMID: 35968694
Chronic consumption of excess ethanol is one of the major risk factors for colorectal cancer (CRC), and the pathogenesis of ethanol-related CRC (ER-CRC) involves ethanol-induced oxidative-stress and inflammation in the...
2.
Ohira H, Tsuruya A, Oikawa D, Nakagawa W, Mamoto R, Hattori M, et al.
PLoS One . 2021 Feb; 16(2):e0246580. PMID: 33577585
Chronic ethanol consumption is a risk factor for colorectal cancer, and ethanol-induced reactive oxygen species have been suggested to play important roles in the pathogenesis of ethanol-related colorectal cancer (ER-CRC)....
3.
Ohira H, Tsutsui W, Fujioka Y
J Atheroscler Thromb . 2017 May; 24(7):660-672. PMID: 28552897
Intestinal flora (microbiota) have recently attracted attention among lipid and carbohydrate metabolism researchers. Microbiota metabolize resistant starches and dietary fibers through fermentation and decomposition, and provide short chain fatty acids...
4.
Ohira H, Tsutsui W, Mamoto R, Yamaguchi S, Nishida M, Ito M, et al.
Lipids Health Dis . 2016 Dec; 15(1):213. PMID: 27938411
Background: Interactions between adipocytes and macrophages are associated with metabolic disorders. Production of pro-inflammatory mediators and the release of free fatty acids (FFAs) increase when these cells are co-cultured; butyrate...
5.
Ohira H, Fujioka Y, Katagiri C, Mamoto R, Aoyama-Ishikawa M, Amako K, et al.
J Atheroscler Thromb . 2013 Mar; 20(5):425-42. PMID: 23470566
Aim: Paracrine interaction between macrophages and adipocytes in obese visceral fat tissues is thought to be a trigger of chronic inflammation. The immunomodulatory effect of the short chain fatty acid,...
6.
Nagata T, Sugiyama D, Kise T, Tsuji S, Ohira H, Sato I, et al.
Lipids Health Dis . 2012 Nov; 11:146. PMID: 23110373
Background: Hypertriglyceridemia and postprandial hyperlipidemia is thought to play an important role in atherosclerosis, but to select patients at high-risk for cardiovascular diseases is difficult with triglycerides (TG) alone in...
7.
Ohira H, Fujioka Y, Katagiri C, Yano M, Mamoto R, Aoyama M, et al.
J Clin Biochem Nutr . 2012 Jan; 50(1):59-66. PMID: 22247602
In inflammatory bowel diseases, interleukin-1β production is accelerated. Butyrate, a short chain fatty acid, plays an important role in inflammatory bowel diseases. We investigated the effect of butyrate on interleukin-1β...
8.
Ikeda M, Ohira H, Toyama Y, Katagiri T, Sakakibara B
J Clin Biochem Nutr . 2008 Feb; 41(3):169-74. PMID: 18299711
To determine why germfree (GF) mice are less productivity of proinflammatory cytokines than conventional (CV) mice, we studied serum levels of interleukin 10 (IL-10) and prostaglandin E(2) (PGE(2)) in mice...
9.
Sakata S, Fujino M, Matsuda K, Maeda M, Ohira H, Kawasaki K, et al.
J Nutr Sci Vitaminol (Tokyo) . 2008 Jan; 53(6):489-95. PMID: 18202536
Liver tyrosine aminotransferase (TAT) activity is known to increase with ethanol treatment; however, the mechanism of this increase is unclear. Upon investigation we found that TAT activity and mRNA levels...
10.
Naemura A, Ohira H, Ikeda M, Koshikawa K, Ishii H, Yamamoto J
Pathophysiol Haemost Thromb . 2007 Jan; 35(5):398-404. PMID: 17230043
Prevention of arterial thrombotic diseases is of high priority in developed countries. As inappropriate diet is regarded as an important risk factor of thrombotic events, daily intake of an antithrombotic...